|Jmol-3D images||Image 1|
|Molar mass||450.65 g/mol|
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Tiomesterone is an anabolic steroid.
Extension of the chain of double bonds in androstenes provides yet another site for modifying the basic structure.
Bromination of the intermediate () that features the 1,4-dien-3-one system proceed on the allylic position at C6 (). Dehydrobromination by means of lithium carbonate in DMF leads to formation of the 1,4,6-trien-3-one system (). Treatment of that intermediate with thioacetic acid proceeds to add one thiol group to each end of the conjugated systems to afford the bisthiolated product thiomestrone ().
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