Thiopurine
From Wikipedia, the free encyclopedia
The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients.
Metabolism is catalyzed by S-methyltransferase.[1]
[edit] See also
- 6-Thioguanine (6-TG)
- 6-Mercaptopurine (6-MP)
- Azathioprine (AZA)
[edit] References
- ^ Sahasranaman S, Howard D, Roy S (August 2008). "Clinical pharmacology and pharmacogenetics of thiopurines". Eur. J. Clin. Pharmacol. 64 (8): 753–67. doi:10.1007/s00228-008-0478-6. ISBN 0022800804786. PMID 18506437.
[edit] External links
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