Thiopurine

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Thioguanine
Mercaptopurine
Azathioprine

The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients.

Metabolism is catalyzed by S-methyltransferase.[1]

See also [edit]

References [edit]

  1. ^ Sahasranaman S, Howard D, Roy S (August 2008). "Clinical pharmacology and pharmacogenetics of thiopurines". Eur. J. Clin. Pharmacol. 64 (8): 753–67. doi:10.1007/s00228-008-0478-6. ISBN [[Special:BookSources/0022800804786|0022800804786 [[Category:Articles with invalid ISBNs]] [[Category:Articles with invalid ISBNs]]]] Check |isbn= value (help). PMID 18506437. 

External links [edit]

Specific antirheumatic products / DMARDs (M01C)
Quinolines
Gold preparations
Other

M: JNT

anat (h/c, u, t, l)/phys

proc, drug (M01C, M4)


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