Thiorphan

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Thiorphan
Thiorphan2DCSD.svg
Systematic (IUPAC) name
(±)-2-[(2-benzyl-3-sulfanyl-propanoyl)amino]acetic acid
Clinical data
Legal status
?
Identifiers
CAS number 76721-89-6 N
ATC code ?
PubChem CID 3132
DrugBank DB08626
ChemSpider 3020 YesY
ChEMBL CHEMBL10247 YesY
Chemical data
Formula C12H15NO3S 
Mol. mass 253.32 g/mol
 N (what is this?)  (verify)

Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]

See also[edit]

References[edit]

  1. ^ a b Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology 125 (1): 147–50. doi:10.1016/0014-2999(86)90094-4. PMID 3015640.