Thomas J. Silhavy

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Thomas J. Silhavy
Born 1948
Died -
Nationality American
Fields molecular biology
Institutions Princeton University
Notable awards Novitski Prize, in 2008

Thomas J. Silhavy is the Warner-Lambert Parke-Davis Professor of molecular biology at Princeton University. Silhavy is a bacterial geneticist who has made fundamental contributions to several different research fields. He is best known for his work on protein secretion, membrane biogenesis, and signal transduction. Using Escherichia coli as a model system, his lab was the first to isolate signal sequence mutations, identify a component of cellular protein secretion machinery, discover an integral membrane component of the outer membrane assembly machinery, and to identify and characterize a two-component regulatory system.[1] Current work in his lab is focused on the mechanisms of outer membrane biogenesis and the regulatory systems that sense and respond to envelope stress and trigger the developmental pathway that allows cells to survive starvation. He is the author of more than 200 research articles and three books.

Silhavy was elected to the National Academy of Sciences in 2005.[2]

Honors[edit]

  • 2011–Present Editor-in-Chief, Journal of Bacteriology[3]
  • 2008 Novitski Prize[4]
  • 2008 Associate Member of the European Molecular Biology Organization (EMBO)[5]
  • 2005 Member of American Academy of Arts and Sciences[6]
  • 2002 Graduate Microbiology Teaching Award from American Society for Microbiology[7]


External links[edit]

References[edit]

  1. ^ http://www.nasonline.org/site/Dir/1945751719?pg=vprof&mbr=1006677&returl=http%3A%2F%2Fwww.nasonline.org%2Fsite%2FDir%2F1945751719%3Fpg%3Dsrch%26view%3Dbasic&retmk=search_again_link retrieved 2010-08-12
  2. ^ http://www.pnas.org/content/102/21/7405/suppl/DC1 retrieved 2010-08-12
  3. ^ http://journals.asm.org/site/misc/announcements_aug11.xhtml retrieved 2012-04-06
  4. ^ *Thorner, Jeremy W (March 2008). "The 2008 Novitski Prize". Genetics 178 (3): 1135–6. doi:10.1534/genetics.104.017831. PMC 2278103. PMID 18385107.  retrieved 2010-08-12
  5. ^ http://www.embo.org/news/press-release-2008/new-embo-members-2008.html retrieved 2010-08-12
  6. ^ http://www.amacad.org/news/new2005.aspx retrieved 2010-08-12
  7. ^ http://asm.org/asm/index.php/professional-development/asm-graduate-microbiology-teaching-award-past-laureates.html retrieved 2010-08-16