Thomas Naum James (born 24 October 1925 in Amory, Mississippi; died 11 September 2010 in Birmingham, Alabama) was a leading American cardiologist during the last half of the twentieth century. He was chairman of the Department of Medicine at the University of Alabama at Birmingham and then president of the University of Texas Medical Branch at Galveston. He is best known for his research in the anatomy of the coronary arteries and the electrical conduction system of the heart. He served as president of the American Heart Association, the International Society and Federation of Cardiology, and the Tenth World Congress of Cardiology. He retired in 2004, and returned to Birmingham, Alabama, where he died in 2010. His greatest influence, however, was upon his grandchildren, within whom he helped instill a drive toward achievement and excellence. His grandson, Thomas Fenner James, continues in his medical footsteps at Dr. James' alma mater, Tulane University.