In his first film role in 2006, aged 14, he played the lead character, Shaun, in This Is England, written and directed by Shane Meadows. On television he played the character Dizzy, a young boy mentored by Adam Solomons (Luke Treadaway), in the 2006 BBC drama series The Innocence Project. The programme was cancelled after eight episodes due to poor ratings and negative reviews. Turgoose's character was in six of the eight episodes. But, in 2008 he was again in a Shane Meadows film, Somers Town, where he co-starred in a comedy role with young Polish actor Piotr Jagiello. Both young actors shared the "Best Actor in a Narrative Feature" award at New York's Tribeca Film Festival. He is in the current film The Scouting Book For Boys, and appeared in This Is England '86, a 4-part TV series for Channel 4 looking at characters from This is England three years on. A year later, he appeared in the three-part series This is England 88, aired just before Christmas 2011, and is set to appear in a further series This is England 90.
He also featured in the TV advertising campaign for Coca-Cola running with the London 2012 Olympic torch.