Tirilazad

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Tirilazad
Tirilazad.png
Systematic (IUPAC) name
(16α)-21-[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]-16-methylpregna-1,4,9(11)-triene-3,20-dione
Clinical data
Legal status
?
Identifiers
CAS number 110101-66-1 N
ATC code N07XX01
PubChem CID 104903
ChemSpider 94673 YesY
UNII YD064E883I YesY
KEGG D08606 YesY
ChEMBL CHEMBL1630578 N
Synonyms (8S,10S,13S,14S,16R,17S)-17-[2-[4-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)piperazin-1-yl]acetyl]-10,13,16-trimethyl-6,7,8,12,14,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
Chemical data
Formula C38H52N6O2 
Mol. mass 624.859 g/mol
 N (what is this?)  (verify)

Tirilazad is a drug proposed to treat acute ischaemic stroke, however results are mixed as to whether the drug truly treats stroke.[1]

Mixed results[edit]

When tested on animal models, tirilazad protects brain tissue, and reduces any brain damage. On the contrary, the drug fails to treat, and even worsens a stroke when studied on a human being.

Usage in treatment of stroke[edit]

Tirilazad currently has no usage in the clinical treatment of stroke.

References[edit]

  1. ^ "Tirilazad for acute ischaemic stroke". Retrieved 2007-07-28.