The Puppet Masters (1951) by Robert A. Heinlein. Titan is the home of an elf-like species, which has been enslaved by parasitic aliens who can control them. These "puppet masters" attempt to take over the Earth by controlling human beings.
First Law (1956), short story by Isaac Asimov. The story is set during a massive storms that strikes Titan regularly and features Mike Donovan, a roboticist who has to deal with a strange incident relevant to an unusual twist of the Three Laws of Robotics. The moon is correctly described as having no magnetic field.
Lucky Starr and the Rings of Saturn (1958), novel by Isaac Asimov. Humans from the Sirius system establish a settlement on Titan as a provocation against the Earth government. Lucky Starr and Bigman Jones have to avert an interstellar war. Also features an emergency landing inside Mimas which is correctly described as mostly ice.
The Game-Players of Titan (1963), novel by Philip K. Dick. A neurotic and suicidal man named Pete Garden must roll a three in Bluff, the game that's become a blinding obsession for the last inhabitants of post-apocalyptic Earth, against opponents who are from Titan.
Perry Rhodan (1960s), German pulp science fiction series. Titan has a prison and advanced medical facilities.
World of Ptavvs (1966), Known Space novel by Larry Niven. Titan is one of the few worlds in the Solar System (along with Earth and Mars), which is not under jurisdiction of the Belt government. It is the site of the Titan Hotel, a honeymoon retreat for wealthy flatlander couples.
Imperial Earth (1976), novel by Arthur C. Clarke. Titan is home to a human colony with a population of 250,000 and provides an important role in the Solar System's economics; Titan's atmosphere supplies the hydrogen needed to support interplanetary travel.
Bio of a Space Tyrant (1983), series by Piers Anthony. Titan has been colonized by the Japanese, whereas Saturn has been colonized by the Russians, Chinese, and other former Asian nations in the post-diaspora future.
Fiasco (1986), novel by Stanisław Lem. The first several chapters are set on Titan, with a character ending up frozen on the surface for several hundred years.
Saturnalia (1986), novel by Grant Callin. Titan is one of the locations of an alien artifact. A fictional volcano, Mons Gargantua is described in the book as being so large as to even dwarf Olympus Mons.
"Saturn's Child" by Nichelle Nichols and Margaret Wander Bonanno. In the late 21st century, Earth's first expedition to Titan discovers a highly evolved race of beings - the Fazisians - from another planet already living there.
Titan (2006), novel by Ben Bova. Part of the Grand Tour series. Titan is being explored by an artificially intelligent rover which mysteriously begins malfunctioning, while a mobile human Space Colony explores the Rings and other moons.
Sombras en Titán (Shadows in Titan) (2006), novel by José Antonio Suárez, features the moon prominently.
"Storm in a T-Suit" (2010), "Hatchway" (2011), "Broadwing" (2011), and "Emptying Roesler" (2013), short stories by Simon Petrie. A sequence exploring future human colonization of Titan.
Communion of Dreams (2012), a novel by Jim Downey. A mysterious alien artifact is discovered on Titan that has strange effects on anyone who observes it.
"A Titan for Christmas", a sci-fi romance novelette released in 2012 by Aria Kane, features a mining engineer who works on Titan and is trying to get home to Earth in time to spend Christmas with her family.
"The Glowing Eggs of Titan" (1962), episode Space Patrol TV series. Husky's discovery of a luminous egg of the Saturnian moon of Titan could prove to be the solution of the Martian energy crisis.
The Invisible Enemy (1977), a Doctor Who serial. Takes place partly on a manned base on Titan in the year 5000, by which time the human race has spread across the galaxy. Titan's methane atmosphere bursts into flames after the Doctor releases vast amounts of oxygen as a trap to destroy an enlarged virus.
Transformers G1 (1985), TV series. In the episode, The God Gambit, a group of people, known as Titans, live on Titan and have a belief in the Sky Gods. However, this is only a ruse from the temple workers to deceive the people and give them harsh laws. Talaria and her group of rebels attempt to stop them. Talaria's group and the people worship the Decepticons when they arrive, who deem themselves as gods and hold Cosmos, who they were chasing, captive. Jazz and Perceptor, with the help of Omega Supreme, rescue Cosmos and Talaria (who Jazz had developed a special relationship with) and free the peoples of the Decepticons' ruse. They rebuild their homes on another side of the moon, as the side with the temple on it was burned.
Creature (The Titan Find) (1985), horror film. Titan is where ancient aliens preserved dormant creatures from all over the galaxy.
Red Dwarf (1988), BBC TV series. The character Lister illegally imports a cat from Titan that, through the action of hard radiation over millions of years, becomes the progenitor of a well-dressed, but not particularly intelligent species called Felis sapiens. In the first series Lister also often sings a song mentioning Titan, as well as Ganymede.
The U.S.S. Titan is the name of William Riker's first command as noted in Star Trek Nemesis. The Titan is a Luna-Class ship, all of which are named after moons in the Terran System, with Starfleet construction number NCC-80102.
Gattaca (1997), film. Titan is the goal for a manned space mission, which is seen lifting off in the final sequence.
Starhunter (2001), TV series. Titan features prominently as the former home of the character Dante, and is the site of a large colony.
Judge Dredd, part of the 2000 AD comic series. Titan is used as a penal colony, but, due to a writer's error, is placed in orbit around Jupiter. This was later explained as being due to a scientific experiment in teleportation. This was revealed in the Games Workshop adventure for the Judge Dredd Roleplaying Game - Judgement Day (Not to be mistaken for the Zombie Takeover) where the Judges discover that the soul of Judge Caligula is still alive and is attempting to take over Megacity 1. The players in their investigation get to go to Titan. In the introduction that tells the GM about Titan, it reveals about the Teleportation Experiment that went wrong. (A fact that was said in the White Dwarf review of this adventure to be a very neat solution to the writer's error.)
"The God Gambit" (1985), episode of Transformers animated cartoon. Titan is home to a primitive civilization of humanoids who worship Transformers as gods.
"Money is Everything" (1986), episode of The Transformers animated cartoon. In the year 2006, Titan has been terraformed by humans.
Cowboy Bebop (1998), anime. Titan was the site of a war over hydrocarbon extraction in the year 2068. It is unclear whether there was a colony on the moon.
Chi-Chian comics, animated series, and a role-playing video game by Voltaire. The albino character Nahm flees from her oppressive childhood on Titan, which is home to a colony of bigoted genetic purists.
In the animated TV show Futurama, titanium mines on Titan cave in, causing the value of titanium to skyrocket, convincing Bender to sell most of his body, save his own head.
Aim for the Top 2! (2004), anime. Titan is the location of the Titan Variable Gravity Well. A living habitat exists on Titan to house the team attempting to extract the artifact as well featuring plush facilities for visiting members of Topless and their Buster Machines.
In the Marvel Comics Universe, Titan is home to a colony of Eternals, a godlike race of men and women created from primitive humans by the powerful 'space gods' the Celestials as part of an experiment, and also spawned the super villain Thanos, and the final resting place of Mar-vell. Also, the Stone men of Saturn briefly lived around Titan.
In the DC Comics Universe, Titan is home to a race of very powerful telepaths, originally genetically adapted Terran immigrants. Depending on what part of the continuity you are reading, they may have been seeded there in the late 20th century as a colony by Lar Gand (variously known as Mon-El, Valor and M'Onel). Among them is 30th century telepath Imra Ardeen (aka Saturn Girl), who appeared as a founding member of the Legion of Super-Heroes in Adventure Comics #247 (April 1958).
In the 1979 anime movie Galaxy Express 999, the 999 makes a stopover on Titan, which has been terraformed to support human life. Titan is a "paradise" planet where there's no rule or no law.
In one Wonder Woman story Titan is shown to be in a state similar to Earth millions of years ago, with dinosaurs and various other pre-historic reptiles on it. Wonder Woman saves a group of caveman and bestows wisdom to them, which she thinks will help them gather civilization.
In Marvel Family #16 the mightiest being of Titan appears. It is metallic, and claims on Titan they eat metal. He is kidnapped by a Plutonian tyrant to fight other beings and is beaten by Captain Marvel.
Level 15 of Descent (1994), as well as its second sequel, Descent 3 (2000), take place on Titan. In Descent the player is in a mine, while in Descent 3 the player travels to a proving ground.
In Starlancer, Titan is the site of a major, decisive battle between Alliance and Coalition forces.
In the PlayStation game Colony Wars, Titan is the base of a Navy supergun. The League destroy Titan in the process of eradicating the weapon.
Titan serves as the final level of the game Solar Eclipse for the Sega Saturn. It is the central front for the LaGrange Mining Operation, which is spread out over Saturn's seven largest moons and controlled by the AI program "IRIS".
The plot of Huygen's Disclosure, published in 1996 by SegaSoft, actually involves not only Titan, but the pending arrival of the Huygens probe. It did not depict Titan realistically.