Widom is the son of Eloise of Coral Springs. He has one brother, Gary, and is married to Beth Eisenberg also of Coral Springs. He is coaching junior tennis players while simultaneously going to school and working to receive his massage therapy license. He is an avid sports fan and in his spare time enjoys golf and fishing.
Widom trains in Pembroke Pines with coach Pierre Arnold, and attended and played at the University of Miami from 2001-2003. During this time, he was recognized as "Most Outstanding Player" at the Big East Tournament and named to the USA Tennis Collegiate Team.
Widom reached a career high singles ranking of 200 in July 2006 and a doubles ranking of 162 in April 2009.
Despite the fact that in three years Widom has suffered from eye cancer, two knee injuries, and inflammation in his elbow, he has recovered and continues to play and travel across the world regularly.
Playing mainly challenger tournaments, Widom achieved his career breakthrough when he won three matches in 2009 to qualify for the SAP Open in San Jose, and went on to beat 44th ranked Robby Ginepri, former 21st ranked Taylor Dent, and lost in three sets to the 21st ranked Radek Štěpánek.
The following month, Widom went back to California and qualified for the ATP Masters 1000 at Indian Wells. He started by beating Iván Navarro in straight sets and eventually lost to 12th ranked David Ferrer.
This turn of events prompted ESPN to report that "a red-headed, blue-eyed journeyman from Coral Springs, Florida, made the largest leap of any player on the ultimate tennis ladder. After a series of outrageous misfortunes, Todd Widom did something extraordinary: He reached the quarterfinals of the SAP Open in San Jose."