On September 4, 1989, Worrell was pitching for his 125th career save, which would have tied him with Bruce Sutter for the Cardinals' career record. While making a pitch, he felt a ligament snap. He underwent elbow surgery in December to repair the damage, then experienced shoulder pain when attempting to come back for the 1991 season and was diagnosed with a rotator cuff tear. As a result, he missed both the 1990 and 1991 seasons due to injuries and rehabilitation. Worrell came back in 1992 as a set-up man for veteran Lee Smith.
Worrell signed as a free agent with the Los Angeles Dodgers on December 9, 1992, where he struggled for two seasons before regaining his old form and saving 32, 44, and 35 games in the final three seasons of his career, making two of his three career All-Star appearances and becoming the Dodgers career saves leader. He retired following the 1997 season.
Todd is also the older brother of Tim Worrell, himself a major league pitcher between 1993-2006, and also a distant relative of American swimmer Michael Worrell. Both attended Biola University. He currently owns and operates Firesteel Creek Hunting Lodge in Plankinton, South Dakota.