Tolfenamic acid

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Tolfenamic acid
Tolfenamic Acid.png
Systematic (IUPAC) name
2-[(3-chloro-2-methylphenyl)amino]benzoic acid)[1]
Clinical data
AHFS/ International Drug Names
13710-19-5 N
PubChem CID 610479
ChemSpider 530683 YesY
KEGG D01183 YesY
Chemical data
Formula C14H12ClNO2
261.707 g/mol
 N (what is this?)  (verify)

Tolfenamic acid (TA) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.

Other possible uses[edit]

A study concludes, "TA was found significantly better than placebo in the subjective evaluation of drug efficacy (p<0.001) and in reducing the reported hangover symptoms in general (p < 0.01). In the TA group, significantly lower symptom scores were obtained for headache (p<0.01), and for nausea, vomiting, irritation, tremor, thirst and dryness of mouth (all p < 0.05)."[1]

Commercial names[edit]

Commercial names for tolfenamic acid include Clotam Rapid, Migrex and Tufnil for use in humans and Tolfedine for veterinary use in cats and dogs. This drug should not be confused with Tolmetin.


  1. ^ a b Kim Vilbour Andersen, Sine Larsen, Børge Alhede, Niels Gelting and Ole Buchardt (1989). = P29890001443 "Characterization of two polymorphic forms of tolfenamic acid, N-(2-methyl-3-chlorophenyl)anthranilic acid: their crystal structures and relative stabilities". J. Chem. Soc., Perkin Trans. 2 (10): 1443–1447. doi:10.1039/P29890001443. 

External links[edit]