He returned to local news as lead anchor for WBFF and WNUV in Baltimore, and then for WGCL-TV in Atlanta, Georgia. Based at CNN Center in Atlanta, Harris co-anchored CNN Saturday Morning and CNN Sunday Morning with Betty Nguyen until he made the move to anchor CNN Newsroom on September 8, 2008. He was also a frequent substitute anchor on weekday news programs including American Morning. Harris has won an Emmy Award.
After Harris criticized NASA for naming the new space station treadmill after comedian Stephen Colbert, Colbert responded on September 30, 2009 by naming his in-studio toilet the H.A.R.R.I.S. (Human Ass Receiving Receptacle In Studio)