Tosufloxacin

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Tosufloxacin
Tosufloxacin.png
Systematic (IUPAC) name
7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Clinical data
AHFS/Drugs.com International Drug Names
Legal status ?
Identifiers
CAS number 100490-36-6 YesY
ATC code None
PubChem CID 5517
UNII GHJ553KQPS N
KEGG D02317 YesY
ChEBI CHEBI:77573 N
ChEMBL CHEMBL273348 N
Chemical data
Formula C19H15F3N4O3 
Mol. mass 404.34 g/mol
 N (what is this?)  (verify)

Tosufloxacin is a fluoroquinolone antibiotic. It has a controversial safety profile in relation to other fluoroquinolones. It is associated with severe thrombocytopenia and nephritis, and hepatotoxicity.[1] It is sold in Japan under the brand name Ozex.

See also[edit]

References[edit]

  1. ^ Rubinstein, E. (2001). "History of quinolones and their side effects.". Chemotherapy. 47 Suppl 3: 3–8; discussion 44–8. doi:10.1159/000057838. PMID 11549783.