TosMIC

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TosMIC[1]
TosMIC-2D-skeletal.png
TosMIC-3D-vdW.png
Names
IUPAC name
1-(isocyanomethylsulfonyl)-4-methylbenzene
Identifiers
36635-61-7 YesY
ChemSpider 142204 YesY
Jmol-3D images Image
PubChem 161915
Properties
C9H9NO2S
Molar mass 195.24 g mol−1
Melting point 109 to 113 °C (228 to 235 °F; 382 to 386 K)
Hazards
R-phrases R23/24/25
S-phrases S36/37 S45
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY verify (what isYesY/N?)
Infobox references

Toluenesulfonylmethyl isocyanide or TOSMIC is an organic compound with the formula CH3C6H4SO2CH2NC. The molecule contains both sulfonyl and isocyanide groups. It is a colourless solid that unlike many isocyanides, is odorless. It is prepared by dehydration of the related formamide derivative. It is used in the Van Leusen reaction which is used to convert aldehydes to nitriles or in the preparation of oxazoles and imidazoles.[2]

References[edit]

  1. ^ p-Toluenesulfonylmethyl isocyanide at Sigma-Aldrich
  2. ^ Hoogenboom, B. E.; Oldenziel, O. H.; van Leusen, A. M. (1977). "p-TOLYLSULFONYLMETHYL ISOCYANIDE". Org. Synth. 57: 102. ; Coll. Vol. 6, p. 987