|Group:||Group III (dsRNA)|
Totiviridae is a family of double-stranded RNA viruses. They are non-enveloped, icosahedral viruses. The virion is composed of a single capsid protein and is about 40 nanometers in diameter. The capsid has a T=2 symmetry.
The genome is composed of a linear double-stranded RNA molecule of 4.6–6.7 kilobases. It contains 2 overlapping open reading frames (ORF)—gag and pol—which respectively encode the capsid protein and the RNA-dependent RNA polymerase. Some totiviruses contain a third small potential ORF.
There are five genera in Totiviridae, which contain a total of 29 species.
- Genus Giardiavirus; type species: Giardia lamblia virus
- Genus Leishmaniavirus; type species: Leishmania RNA virus 1-1
- Genus Totivirus; type species: Saccharomyces cerevisiae virus L-A
- Genus Trichomonasvirus; type species: Trichomonas vaginalis virus 1
- Genus Victorivirus: type species Helminthosporium victoriae virus 190S
Another virus in this group - Infectious myonecrosis virus - has not yet been placed into a genus.
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