Transfer factor

For transfer factors in mathematics, see fundamental lemma (Langlands program).

Transfer factors are immune molecules that cause antigen-specific cell-mediated immunity, primarily delayed hypersensitivity and the production of lymphokines, as well as binding to the antigens themselves. They have a molecular weight of approximately 5000 Daltons and are composed entirely of amino acids. Transfer factors were discovered by Henry Sherwood Lawrence. They are promoted as being able to cure a variety of conditions, though they have not been proven to work.

Uses

Transfer factors have been promoted as a treatment for a large number of diseases and health concerns but have not been proven effective in the treatment of most of these conditions. It may help immunize children with leukemia against shingles. The United States Food and Drug Administration regulates transfer factors as a dietary supplement and has issued a warning notice to a website selling transfer factors that they have not been proven to be effective or safe in the treatment of any condition, nor have there been any biological licenses or New Drug Applications produced for the substance.

Side effects

Human-derived transfer factor appears to be safe for use (though ineffective) for up to two years and bovine-derived transfer factor for up to three months. Side effects include fever and swelling and pain at the injection site. Concern has been raised over the possibility of catching Bovine spongiform encephalopathy (Mad Cow Disease) or other diseases from animal-derived products. Transfer factors are contraindicated for women who are pregnant or breastfeeding.

See also

• Lymphokine

External links

• MeSH Transfer+factor