Transrail Freight was created in 1994 along with Mainline Freight and Loadhaul as part of the broadly regional split of British Rail's Trainload Freight trainload freight operations - Transrail Freight had the largest operating area of the three companies, operating in Scotland and the entire west of England (south west, west midlands, and north west), as well as Wales. Three companies were created with the aim of promoting competition between the businesses. It was initially and briefly named "Trainload Freight West Limited" before being re-branded in Jul 1994.
Transrail had the largest inherited operating area of the three post-Trainload Freight companies, but the smaller initial traffic of the three. The company initiated a long distance wagonload train service branded 'Enterprise', later operated by EWS as the 'EWS Enterprise' service.