Tremont, was originally part of Brooklyn Township and from 1836 until 1854 was a section of what is now its sister neighborhood, Ohio City, when the latter was an independent town. Both were later annexed by the city of Cleveland, but Tremont remained 1867. During the early 1850s, the now defunct Cleveland University briefly occupied a section of Tremont, and in fact before being named Tremont the neighborhood was briefly known as University Heights (not to be confused with the eastern Cleveland suburb of the same name). Vestiges of the neighborhood's days as a college town remain, however, in streets with scholarly names, such as Professor, Literary, College and University.  The early 20th century saw an influx of Ukrainian immigrants who sought work in the steel mills in the area, and by the 1920s Tremont was home to over 35,000 residents.By the 1960s, however, the population had begun to steadily decline. With the loss of manufacturing jobs particularly in Cleveland's steel industry, culminating in the recession of the early 1980s, Tremont's population dwindled. By the 2000 census there were fewer than 9,000 residents.
Since the early 2000s, Tremont has reinvented itself and is experiencing a revival. With its close proximity to downtown and affordable dwellings, the neighborhood began a revival in the 1990s due in large part to an influx of new residents, including young professionals, empty nesters, hipsters and immigrants attracted to the neighborhood's amenities, historic housing stock and new infill housing. Tremont has become a destination spot with numerous restaurants, shops, and art galleries. The Tremont Art Walk occurs on the 2nd Friday of each month.
In 2013, it was learned that three women had been held captive in a house on Seymour Avenue for at least ten years. 
Neighborhood landmarks and points of interest
Lemko Hall (2337 W. 11th St.) - The historic hall served as a social gathering place for the one-time sizable concentration of immigrants from the Slavic region of Lemkovina who lived in Tremont. Today it is a mixed use (retail and condominiums) structure and a city landmark. It is arguably most famous for being the site of the wedding reception in the 1978 film, The Deer Hunter.
Lolita (900 Literary Road) - Iron Chef Winner, Michael Symon's bistro is one of a number of standout neighborhood eateries.
A Christmas Story House (3159 West 11th Street) - Site of several exterior scenes in the 1983 holiday film, A Christmas Story, the house was home to protagonist Ralphie Parker and his family. It was purchased on eBay in 2004 by San Diego entrepreneur Brian Jones and subsequently renovated to replicate the interior and exterior as seen in the film, and is now a museum.
Steelyard Commons Shopping Center (3447 Steelyard Drive) - A multi-tenant retail shopping center, constructed in 2007 on the former site of an LTV Steel mill. Featured national retailers including The Home Depot, Target, and a Walmart Superstore.
T.R.E.A.T.S (Tremont Residents Empowering Animals To Socialize) Dog Park Located at Clark Field - the largest off-leash canine play park in the Cleveland area.
The Chelsea Building is one of the oldest high rise building constructed in Cleveland, being erected in 1898. The building also has the first residential elevator installed in the city.