Treponema denticola

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Treponema denticola
Scientific classification e
Domain: Bacteria
Phylum: Spirochaetes
Order: Spirochaetales
Family: Spirochaetaceae
Genus: Treponema
Species: T. denticola

Treponema denticola is a Gram-negative, obligate anaerobic, motile and highly proteolytic spirochete bacterium. It dwells in a complex and diverse microbial community within the oral cavity and is highly specialized to survive in this environment. T. denticola is associated with the incidence and severity of human periodontal disease. Elevated T. denticola levels in the mouth is considered one of the main etiological agents of periodontitis. [1] T. denticola is related to the syphilis-causing obligate human pathogen, Treponema pallidum subsp. pallidum.

See also[edit]


  1. ^ Jobin M-C et al. (2008). "The Molecular Biology of the Survival and Virulence of Treponema denticola". Molecular Oral Microbiology. Caister Academic Press. ISBN 978-1-904455-24-0. 

Further Reading[edit]

Miller, D.P.; Frederick, J.R.; Sarkar, J.; Marconi, R.T. (24 Jul 2014). "The Treponema denticola AtcR LytTR domain-containing response regulator interacts with three architecturally distinct promoter elements: implications for understanding the molecular signaling mechanisms that drive the progression of periodontal disease". Molecular Oral MIcrobiology 29 (5): 219–232. doi:10.1111/omi.12059. Retrieved 6 Nov 2014.