Triethylenemelamine

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Triethylenemelamine

Systematic (IUPAC) name
2,4,6-Tris(aziridin-1-yl)-1,3,5-triazine
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	51-18-3^Y
ATC code	?
PubChem	CID 5799
UNII	F7IY6HZG9D^N
KEGG	C07642^N
ChEMBL	CHEMBL502384^N
Chemical data
Formula	C₉H₁₂N₆
Mol. mass	204.23 g/mol
N (what is this?) (verify)

Triethylenemelamine is a drug used in chemotherapy.

It can cause chromatid aberrations.^[1]

[edit] See also

Altretamine

[edit] References

^ Luippold HE, Gooch PC, Brewen JG (February 1978). "The production of chromosome aberrations in various mammalian cells by triethylenemelamine". Genetics 88 (2): 317–26. PMC 1213803. PMID 565312. http://www.genetics.org/cgi/pmidlookup?view=long&pmid=565312.

Intracellular chemotherapeutic agents / antineoplastic agents (L01)

SPs/MIs
(M phase)

Block microtubule assembly	Vinca alkaloids (Vinblastine Vincristine Vinflunine Vindesine Vinorelbine)

Block microtubule disassembly	Taxanes (Cabazitaxel Docetaxel Larotaxel Ortataxel Paclitaxel Tesetaxel) Epothilones (Ixabepilone)

DNA replication
inhibitor

DNA precursors/
antimetabolites
(S phase)

Folic acid	Dihydrofolate reductase inhibitor (Aminopterin Methotrexate Pemetrexed Pralatrexate) Thymidylate synthase inhibitor (Raltitrexed Pemetrexed)

Purine	Adenosine deaminase inhibitor (Pentostatin) Halogenated/ribonucleotide reductase inhibitors (Cladribine Clofarabine Fludarabine) Thiopurine (Thioguanine Mercaptopurine)

Pyrimidine	Thymidylate synthase inhibitor (Fluorouracil Capecitabine Tegafur Carmofur Floxuridine) DNA polymerase inhibitor (Cytarabine) Ribonucleotide reductase inhibitor (Gemcitabine) Hypomethylating agent (Azacitidine Decitabine)

Deoxyribonucleotide	Ribonucleotide reductase inhibitor (Hydroxycarbamide)

Topoisomerase inhibitors
(S phase)

I	Camptotheca (Camptothecin Topotecan Irinotecan Rubitecan Belotecan)

II	Podophyllum (Etoposide Teniposide)

II+Intercalation	Anthracyclines (Aclarubicin Daunorubicin Doxorubicin Epirubicin Idarubicin Amrubicin Pirarubicin Valrubicin Zorubicin) Anthracenediones (Mitoxantrone Pixantrone)

Crosslinking of DNA
(CCNS)

Alkylating	Nitrogen mustards: Mechlorethamine Cyclophosphamide (Ifosfamide Trofosfamide) Chlorambucil (Melphalan Prednimustine) Bendamustine Uramustine Estramustine Nitrosoureas: Carmustine Lomustine (Semustine) Fotemustine Nimustine Ranimustine Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan Treosulfan) Aziridines: Carboquone ThioTEPA Triaziquone Triethylenemelamine

Alkylating-like	Platinum (Carboplatin Cisplatin Nedaplatin Oxaliplatin Triplatin tetranitrate Satraplatin)

Nonclassical	Hydrazines (Procarbazine) Triazenes (Dacarbazine Temozolomide) Altretamine Mitobronitol

Intercalation	Streptomyces (Actinomycin Bleomycin Mitomycin Plicamycin)

Photosensitizers/PDT

Other

Enzyme inhibitors	FI (Tipifarnib) CDK inhibitors (Alvocidib Seliciclib) PrI (Bortezomib) PhI (Anagrelide) IMPDI (Tiazofurine) LI (Masoprocol) PARP inhibitor (Olaparib) HDAC (Panobinostat Vorinostat Romidepsin)

Receptor antagonists	ERA (Atrasentan) Retinoid X receptor (Bexarotene) Sex steroid (Testolactone)

Other/ungrouped	Amsacrine Trabectedin Retinoids (Alitretinoin Tretinoin) Arsenic trioxide Asparagine depleters (Asparaginase/Pegaspargase) Celecoxib Demecolcine Elesclomol Elsamitrucin Etoglucid Lonidamine HAMLET (human alpha-lactalbumin made lethal to tumor cells) Lucanthone Mitoguazone Mitotane Oblimersen Omacetaxine mepesuccinate mTOR inhibitors (Everolimus Temsirolimus)

tumr, epon, para

drug (L1i/1e/V03)

This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it.

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