Tristine Skyler (born July 27, 1971) is an American writer and producer. She was born and raised in New York City, where she began her career as an actor, performing in television, in movies as well as in the theater. She is the sister of Edward Skyler, former Deputy Mayor of Operations for Mayor Michael R. Bloomberg, the youngest Deputy Mayor in city history, who is now Executive Vice President of Global Affairs for Citigroup.
 Skyler is the author of the play "The Moonlight Room", about at-risk youth in New York City, which she co-produced at the TriBeCa Playhouse in 2003 before transferring to a commercial run Off-Broadway on Theater Row. It was named one of the 'Ten Best Plays of the Year' by The New York Times and The New York Post, and has since been performed all over the country. Previously she co-wrote the feature film Getting to Know You, adapted from short stories by Joyce Carol Oates, which starred Zach Braff, Chris Noth, Heather Matarazzo and Bebe Neuwirth. It played in the Dramatic Competition at the Sundance Film Festival, the 'Critics Week' section of the Venice Film Festivals, and received "Two Thumbs Up" from Ebert and Roeper.
In 2005, the actress Julia Stiles hired her to adapt Sylvia Plath's iconic novel The Bell Jar for the screen. She is currently the executive producer of a film adaptation of Robert Kanigel's acclaimed biography "The Man Who Knew Infinity- A Life of the Genius Ramanujan" about the self-taught Indian math genius Srinivasa Ramanujan, whose work is considered the foundation of the digital age, starring Dev Patel and Jeremy Irons. The film completed principal photography in September 2014. It also stars Toby Jones and Stephen Fry.
Skyler is a founding committee member of the Kristen Ann Carr Fund, the first charity dedicated to sarcoma research. She is a member of the advisory board of WIE, a women's issue organization and annual symposium, and has also written for the Huffington Post. She received her B.A. cum laude from Princeton University.