Troponin C type 1

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Troponin C type 1 (slow)
Protein TNNC1 PDB 1aj4.png
PDB rendering based on 1aj4.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols TNNC1 ; CMD1Z; CMH13; TN-C; TNC; TNNC
External IDs OMIM191040 MGI98779 HomoloGene55728 ChEMBL: 2066 GeneCards: TNNC1 Gene
RNA expression pattern
PBB GE TNNC1 209904 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7134 21924
Ensembl ENSG00000114854 ENSMUSG00000091898
UniProt P63316 P19123
RefSeq (mRNA) NM_003280 NM_009393
RefSeq (protein) NP_003271 NP_033419
Location (UCSC) Chr 3:
52.49 – 52.49 Mb
Chr 14:
31.21 – 31.21 Mb
PubMed search [1] [2]

Troponin C, slow skeletal and cardiac muscles is a protein that in humans is encoded by the TNNC1 gene.[1]


Interactions[edit]

Troponin C type 1 has been shown to interact with TNNI3.[2][3][4][5][6]

References[edit]

  1. ^ "Entrez Gene: TNNC1 troponin C type 1 (slow)". 
  2. ^ Ward, Douglas G; Brewer Susan M; Gallon Clare E; Gao Yuan; Levine Barry A; Trayer Ian P (May 2004). "NMR and mutagenesis studies on the phosphorylation region of human cardiac troponin I". Biochemistry (United States) 43 (19): 5772–81. doi:10.1021/bi036310m. ISSN 0006-2960. PMID 15134451. 
  3. ^ Ward, Douglas G; Brewer Susan M; Calvert Melanie J; Gallon Clare E; Gao Yuan; Trayer Ian P (Apr 2004). "Characterization of the interaction between the N-terminal extension of human cardiac troponin I and troponin C". Biochemistry (United States) 43 (13): 4020–7. doi:10.1021/bi036128l. ISSN 0006-2960. PMID 15049709. 
  4. ^ Ward, Douglas G; Brewer Susan M; Cornes Michael P; Trayer Ian P (Sep 2003). "A cross-linking study of the N-terminal extension of human cardiac troponin I". Biochemistry (United States) 42 (34): 10324–32. doi:10.1021/bi034495r. ISSN 0006-2960. PMID 12939162. 
  5. ^ Wang, Xu; Li Monica X; Sykes Brian D (Aug 2002). "Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil". J. Biol. Chem. (United States) 277 (34): 31124–33. doi:10.1074/jbc.M203896200. ISSN 0021-9258. PMID 12060657. 
  6. ^ Li, Monica X; Saude Erik J; Wang Xu; Pearlstone Joyce R; Smillie Lawrence B; Sykes Brian D (Jul 2002). "Kinetic studies of calcium and cardiac troponin I peptide binding to human cardiac troponin C using NMR spectroscopy". Eur. Biophys. J. (Germany) 31 (4): 245–56. doi:10.1007/s00249-002-0227-1. ISSN 0175-7571. PMID 12122471. 

Further reading[edit]

External links[edit]