U.S. Route 80 (Alternate) in El Paso ran southbound from the junction of Farm To Market Road 260 and U.S. 80, following Doniphan Drive through the former community of White Spur  (now part of Northwest El Paso). The route continued southbound until Doniphan Drive ended at Paisano Drive, in Smeltertown. U.S. 80 (Alternate), and Paisano drive then followed the tracks of the Atchison, Topeka and Santa Fe Railway along the eastern bank of the Rio Grande until Union Station in Downtown El Paso. U.S. 80 (Alternate) then rejoined U.S. 80 at Texas Avenue in Downtown El Paso. U.S. Route 85 now follows this routing from Paisano Drive's current junction with Interstate 10.
U.S. Route 80 Truck, cosigned with U.S. Route 79 Truck, is a truck route of U.S. 80 through Minden. The route begins at the intersection of Sheppard Street and Shreveport Road, and heads in an eastern direction towards U.S. 80's current alignment along Union Street. Truck U.S. 80 ends at the intersection with mainline US 80, but Truck U.S. 79 follows U.S. 80's alignment, then turns north at an intersection with LA 531.
U.S. Route 80 Truck, cosigned with Louisiana Highway 799, is a truck route of U.S. 80 through Gibsland. It follows the route of LA 799, allowing truck traffic to avoid the downtown part of Gibsland. It begins at an intersection with US 80, known as South Third Street, where US 80 turns to the north, following South Main Street, which is also LA 154. Truck US 80 follows South Third Street, turning north along Gibbs Street. Truck US 80 ends at an intersection with South First Street.
U.S. Route 80 Truck, cosigned with Louisiana Highway 798-1 and Louisiana Highway 151, is a truck route of U.S. 80 through Arcadia. It follows the route of LA 798-1, allowing truck traffic to avoid the main street of Arcadia. US 80 Truck begins at an intersection with US 80, LA 9, and LA 519. It follows LA 798-1 along Second Street, which is less commercialized than US 80 one block to the south. US 80 Truck then turns south to follow LA 151 until the intersection with US 80.