Tuaminoheptane
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| Systematic (IUPAC) name | |
| heptan-2-amine | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 123-82-0  |
| ATC code | R01AA11 |
| PubChem | CID 5603 |
| ChemSpider | 5401  |
| UNII | Z0420GYD84 |
| KEGG | D07371 |
| ChEMBL | CHEMBL123693 |
| Chemical data | |
| Formula | C7H17N |
| Mol. mass | 115.217 g/mol |
| SMILES | eMolecules & PubChem |
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Tuaminoheptane (or tuamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.[1] However, it can cause skin irritation,[2] which limits its usefulness as a nasal decongestant. Side effects can include acute glaucoma, tachycardia and hypertension.[3]
Tuaminoheptane is contained in the 2011 list of prohibited substances published by the World Anti-Doping Agency.
[edit] See also
[edit] References
- ^ Delicado, E. G.; Fideu, M. D.; Miras-Portugal, M. T.; Pourrias, B.; Aunis, D. (1990). "Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells". Biochemical Pharmacology 40 (4): 821–825. doi:10.1016/0006-2952(90)90322-C. PMID 2386550.
- ^ Raoux, M.; Colomban, C.; Delmas, P.; Crest, M. (2007). "The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes". Molecular Pharmacology 71 (6): 1685–1694. doi:10.1124/mol.106.033324. PMID 17384225.
- ^ "Tuaminoheptane Sulfate". BIAM. 24 November 2003. http://www.biam2.org/www/Sub2823.html.
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