Tuataric acid

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Tuataric acid
Molecular formula C8H12O2
Appearance Colorless Solid
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Tuataric acid is an organic compound and an unsaturated carboxylic acid. This colourless compound was isolated in 2009 from the cloacal glands of the tuatara, a lizard-like reptile native to New Zealand. Its formal name is (4E,6Z)-Octa-4,6-dienoic acid, and it consists of an unusual pair of conjugated alkene units with the E and Z configurations.[1]

Tuataric acid can be prepared from pent-4-yn-1-ol through a sequence that begins with the extension of the alkyne terminus by hydroboration and ends with the oxidation of the alcohol.


  1. ^ “Composition of the cloacal gland secretion of tuatara,Sphenodon punctatus” Chemistry & biodiversity 2009, volume 6, pp. 1-37. doi:10.1002/cbdv.200800265