The project was first conceived in 1999 and called the Oklahoma Centennial Botanical Garden Research and Education Center. The Osage Nation conducted a blessing ceremony for the garden in 2007. A 7 acre lake and 1,200 square foot visitor center were dedicated in 2008 and opened to the public in 2009. F. Todd Lasseigne was named to run the garden in 2011. In 2013, some 1,200 plants were added, and the facility was renamed as the Tulsa Botanic Garden. Development continued during the following winter in preparation for the garden's April 2014 reopening.