|— City —|
|• Total||0.7 sq mi (1.9 km2)|
|• Land||0.7 sq mi (1.9 km2)|
|• Water||0.0 sq mi (0.0 km2)|
|Elevation||1,978 ft (603 m)|
|• Density||971.2/sq mi (375.0/km2)|
|Time zone||Central (CST) (UTC-6)|
|• Summer (DST)||CDT (UTC-5)|
|GNIS feature ID||1348931|
Tuscola is located at .(32.209060, -99.797126)
According to the United States Census Bureau, the city has a total area of 0.7 square miles (1.9 km²), all of it land.
As of the census of 2000, there were 714 people, 273 households, and 202 families residing in the city. The population density was 971.2 people per square mile (372.5/km²). There were 307 housing units at an average density of 417.6 per square mile (160.2/km²). The racial makeup of the city was 97.20% White, 0.14% African American, 0.28% Native American, 0.14% Asian, 0.70% from other races, and 1.54% from two or more races. Hispanic or Latino of any race were 7.28% of the population.
There were 273 households out of which 37.4% had children under the age of 18 living with them, 61.5% were married couples living together, 10.6% had a female householder with no husband present, and 26.0% were non-families. 23.8% of all households were made up of individuals and 12.8% had someone living alone who was 65 years of age or older. The average household size was 2.62 and the average family size was 3.08.
In the city the population was spread out with 28.6% under the age of 18, 7.3% from 18 to 24, 27.9% from 25 to 44, 23.4% from 45 to 64, and 12.9% who were 65 years of age or older. The median age was 37 years. For every 100 females there were 89.9 males. For every 100 females age 18 and over, there were 87.5 males.
The median income for a household in the city was $38,068, and the median income for a family was $42,396. Males had a median income of $31,484 versus $21,845 for females. The per capita income for the city was $18,661. About 3.7% of families and 6.8% of the population were below the poverty line, including 5.5% of those under age 18 and 15.7% of those age 65 or over.
Notable people 
- Colt McCoy, former quarterback for the University of Texas Longhorns and a current quarterback for the Cleveland Browns.
- Ed Sprinkle, former American football player and coach.
- "American FactFinder". United States Census Bureau. Retrieved 2008-01-31.
- "US Board on Geographic Names". United States Geological Survey. 2007-10-25. Retrieved 2008-01-31.
- "US Gazetteer files: 2010, 2000, and 1990". United States Census Bureau. 2011-02-12. Retrieved 2011-04-23.