From Wikipedia, the free encyclopedia
  (Redirected from Tyrima)
Jump to: navigation, search
CX157 structure.svg
Systematic (IUPAC) name
3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiine 10,10-dioxide
Clinical data
Legal status
  • Uncontrolled
Routes Oral
ATC code None
PubChem CID 18687754
ChemSpider 13701383 YesY
Chemical data
Formula C14H8F4O4S 
Mol. mass 348.27 g/mol
 YesY (what is this?)  (verify)

CX157 (proposed trade name TriRima, formerly Tyrima) is a selective and reversible inhibitor of MAO-A (RIMA).[1] As of 2007 it was in phase II clinical trials for the treatment of depression.[2]

See also[edit]


  1. ^ Fielding R, Mielach F, Free J, Pande A (2007). "Pharmacokinetics and oral bioavailability of CX157, a reversible selective MAO-A inhibitor, in primates". 2007 AAPS Annual Meeting & Exposition. Retrieved 2009-06-14. 
  2. ^ NCT00739908