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Ubiquitin-like modifier activating enzyme 5
Protein UBA5 PDB 3GUC.png
Rendering based on PDB 3GUC.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols UBA5 ; THIFP1; UBE1DC1
External IDs OMIM610552 MGI1913913 HomoloGene11738 GeneCards: UBA5 Gene
RNA expression pattern
PBB GE UBE1DC1 218289 s at tn.png
More reference expression data
Species Human Mouse
Entrez 79876 66663
Ensembl ENSG00000081307 ENSMUSG00000032557
UniProt Q9GZZ9 Q8VE47
RefSeq (mRNA) NM_024818 NM_025692
RefSeq (protein) NP_079094 NP_079968
Location (UCSC) Chr 3:
132.37 – 132.4 Mb
Chr 9:
104.05 – 104.06 Mb
PubMed search [1] [2]

Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.[1][2][3]

This gene encodes a member of the E1-like activating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[3]


  1. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. 
  2. ^ Komatsu M, Chiba T, Tatsumi K, Iemura S, Tanida I, Okazaki N, Ueno T, Kominami E, Natsume T, Tanaka K (May 2004). "A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier". EMBO J 23 (9): 1977–86. doi:10.1038/sj.emboj.7600205. PMC 404325. PMID 15071506. 
  3. ^ a b "Entrez Gene: UBE1DC1 ubiquitin-activating enzyme E1-domain containing 1". 

Further reading[edit]