The club was originally founded as farm team of UD Salamanca, being named Club Deportivo Salmantino. In 1997 both entities merged, the team was renamed Unión Deportiva Salamanca B, became the main side's reserve team and started competing in Tercera División. With the dissolution of UD Salamanca on 18 June 2013 due to accumulated debts, Salamanca B also dissolved with the main side, immediately after it was forcibly relegated to the Primera División Regional of Castila & León. A new club was later formed, taking the name Club de Fútbol Salmantino. It now plays in Tercera División Group VIII.