UQCRC2

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Ubiquinol-cytochrome c reductase core protein II
Identifiers
Symbols UQCRC2 ; MC3DN5; QCR2; UQCR2
External IDs OMIM191329 MGI1914253 HomoloGene37764 GeneCards: UQCRC2 Gene
EC number 1.10.2.2
RNA expression pattern
PBB GE UQCRC2 212600 s at tn.png
PBB GE UQCRC2 200883 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7385 67003
Ensembl ENSG00000140740 ENSMUSG00000030884
UniProt P22695 Q9DB77
RefSeq (mRNA) NM_003366 NM_025899
RefSeq (protein) NP_003357 NP_080175
Location (UCSC) Chr 16:
21.96 – 21.99 Mb
Chr 7:
120.64 – 120.66 Mb
PubMed search [1] [2]

Cytochrome b-c1 complex subunit 2, mitochondrial is a protein that in humans is encoded by the UQCRC2 gene.[1][2][3]

Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial cytochrome b) and ten nuclear genes: UQCRC1, UQCRC2, Cytochrome c1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and "Rieske-associated protein".


References[edit]

  1. ^ Duncan AM, Ozawa T, Suzuki H, Rozen R (Feb 1994). "Assignment of the gene for the core protein II (UQCRC2) subunit of the mitochondrial cytochrome bc1 complex to human chromosome 16p12". Genomics 18 (2): 455–6. doi:10.1006/geno.1993.1500. PMID 8288258. 
  2. ^ Hosokawa Y, Suzuki H, Toda H, Nishikimi M, Ozawa T (Sep 1989). "Complementary DNA encoding core protein II of human mitochondrial cytochrome bc1 complex. Substantial diversity in deduced primary structure from its yeast counterpart". J Biol Chem 264 (23): 13483–8. PMID 2547763. 
  3. ^ "Entrez Gene: UQCRC2 ubiquinol-cytochrome c reductase core protein II". 

Further reading[edit]