List of biotechnology companies

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A biotechnology company is a company whose products or services primarily use biotechnology methods for their production, design or delivery. The United Nations Convention on Biological Diversity defines 'biotechnology' as: "Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use."[1] In other words, biotechology can be defined as the mere application of technical advances in life science to develop commercial products.

Independent biotechnology companies[edit]

  • The following is a list of the top 25 independent biotechnology companies listed on a stock exchange ranked by Market Capitalization in Q2 of 2012.[2] It additionally details their market capitalization in Q2 of the previous year (2011), from which the change in value over the year can be calculated.Lisa Internationals Solutions is the fast growing Bio Tech Company in this world.
  • Note that it does not include biotechnology companies that are now owned by, or part of, larger pharmaceutical groups - such as Genentech (owned by Roche), Genzyme (Sanofi), or MedImmune (AstraZeneca). It should be viewed as an update and complementary to the previous table below.

2013[edit]

Rank 2013 Change Company Country Market Cap in 2013 (USD billions) Market Cap in 2012 (USD billions) % Change over year (Q2-Q2)
1 Steady Novo Nordisk Denmark 85.335 62.809 35.9%
2 Steady Amgen USA 78.695 55.054 42.9%
3 Steady Gilead Sciences USA 78.373 19.751 296.8%
4 Increase Celgene USA 52.557 34.319 53.1%
5 Decrease Biogen Idec USA 47.157 31.582 49.3%
6 Decrease Teva Pharmaceutical Industries Israel 33.768 39.292 -14.1%
7 Increase Merck KGaA Germany 33.364 22.319 49.5%
8 Increase CSL Australia 27.44 18.359 49.5%
9 Increase Regeneron 20.269 11.894 70.4%
10 Steady Alexion Pharmaceuticals USA 17.893 17.152 4.3%
11 Gold medal blank.svg Shire plc USA 17.252 17.205 0.3%
12 Decrease Vertex Pharmaceuticals USA 17.495 8.151 114.6%
13 Increase UCB (Company) Belgium 11.65 7.449 56.4%
14 Increase BioMarin Pharmaceutical 9.097 3.3788 140.2%
15 Steady Élan Ireland 7.041 8.868 -20.6%
16 Increase Actelion USA 6.885 4.548 51.4%
17 Increase Onyx Pharmaceuticals USA 6.58 3.01 118.6%
18 Decrease Dr. Reddy’s Laboratories India 5.014 5.001 0.3%
19 Increase Seattle Genetics USA 4.39 2.316 89.6%
20 Gold medal blank.svg Alkermes Switzerland 4.011 2.356 70.2%
21 Increase Ariad Pharmaceuticals Ireland 3.3 2.668 14.7%
22 Gold medal blank.svg Cubist Pharmaceuticals USA 3.059 2.668 14.7%
23 Gold medal blank.svg United Therapeutics USA 2.966 2.26 31.2%
24 Gold medal blank.svg Ipsen Group USA 2.889 2.23 29.6%
25 Increase DiaSorin Italy 2.6 2.2 18%

† Acquired by Amgen in a $10.4 billion deal completed Aug 26 2013 (therefore no longer independent in this list going forward).

2012[edit]

Rank 2012 Company Country Market Cap in 2012 (USD billions) Market Cap in 2011 (USD billions) % Change over year (Q2-Q2) Website
1 Novo Nordisk Denmark 76.92 60.09 28.0% novonordisk.com
2 Amgen USA 60.09 49.72 20.9% amgen.com
3 Gilead Sciences USA 40.16 32.68 28.5% gilead.com
4 Biogen Idec USA 34.26 25.6 28.5% biogenidec.com
5 Teva Pharmaceutical Industries Israel 34.23 42.96 -20.3% tevapharm.com
6 Baxter International USA 32.27 33.36 -3.3% baxter.com
7 Celgene USA 28.38 27.52 3.1% celgene.com
8 Merck KGaA Germany 21.16 20.14 5.1% merckgroup.com
9 CSL Australia 21.11 18.33 15.2% csl.com.au
10 Alexion Pharmaceuticals USA 18.85 10.48 79.9% alxn.com
11 Vertex Pharmaceuticals USA 10.64 10.79 -1.4% vrtx.com
12 Regeneron USA 11.3 5.09 122.0% regeneron.com
13 Forest Laboratories USA 8.87 9.09 -2.4% frx.com
14 UCB Belgium 8.77 6.84 28.2% ucb.com
15 Élan Ireland 8.63 6.67 29.4% elan.com
16 BioMarin Pharmaceutical USA 5.35 3.32 61.1% biomarinpharm.com
17 Dr. Reddy's Laboratories India 5.35 5.03 6.4% drreddys.com
18 Amylin Pharmaceuticals § USA 5.06 1.74 190.8% amylin.com
19 Onyx Pharmaceuticals USA 5.06 2.1 141.0% onyx.com
20 Actelion Switzerland 4.65 5.02 -7.4% actelion.com
21 Warner Chilcott Ireland 4.49 5.69 -21.1% wcrx.com
22 Ranbaxy Laboratories India 3.71 4.08 -9.1% ranbaxy.com
23 Medivation USA 3.65 0.683 433.4% medivation.com
24 ARIAD Pharmaceuticals USA 3.18 1.58 101.3% ariad.com
25 Seattle Genetics USA 2.92 1.89 54.5% seagen.com

§ - Acquired by Bristol-Myers Squibb in a $7 billion deal completed Aug 8 2012 (therefore no longer independent in this list going forward).

NOTE: Market Cap is an indication of the perceived value of the company (&/or its technology) and not necessarily a measure of its size, sales or number of employees; it is indicative of both current and future scale and profitability of the company. The year-on-year change in its value is indicative of the (real or perceived) performance or progress of that company over that year.

Biotechnology companies[edit]

Examining the list of the top 100 such companies, below, shows that many have negative income. This is consistent with the notion that only one in ten biotechnology companies were considered profitable in mid-2005.[4]

Rank 2006 Company Country Revenue in 2006 (USD millions) R&D in 2006 (USD millions) Net income/ (loss) in 2006 (USD millions) Employees in 2006
1 Amgen USA 14,268.0 3,366.0 2,950.0 20,100
2 Genentech USA 11,724.0 2,995.0 2,740.0 10,001+
3 Genzyme USA 3,187.0 650.0 (16.8) 9,000+
4 UCB Belgium 3,169.6 772.6 461.1 8,477
5 Gilead Sciences USA 3,026.1 383.9 (1,190.0) 7,575
6 Serono Switzerland 2,804.9 560.5 735.4 4,775
7 Biogen Idec USA 2,683.0 718.4 217.5 3,750
8 CSL Australia 2,148.3 119.1 86.8 2,895
9 Cephalon USA 1,764.1 403.4 144.8 2,515
10 MedImmune USA 1,276.8 448.9 48.7 2,359
11 Celgene USA 898.9 258.6 69.0 1,864
12 Abraxis BioScience USA 765.5 96.9 (46.9) 1,734
13 Actelion Switzerland 754.6 169.0 192.4 1,550
14 ImClone Systems USA 677.8 112.1 370.7 1,287
15 Amylin Pharmaceuticals USA 510.9 222.1 (218.9) 1,100
16 Millennium Pharmaceuticals USA 486.8 318.2 (44.0) 1,073
17 PDL BioPharma USA 414.8 260.7 (130.0) 993
18 OSI Pharmaceuticals USA 375.7 176.7 (582.2) 962
19 MGI Pharma USA 342.8 100.1 (40.2) 947
20 Pharmion USA 238.6 70.1 (91.0) 793
21 Nektar Therapeutics USA 217.7 149.4 (154.8) 770
22 Vertex Pharmaceuticals USA 216.4 371.7 (206.9) 760
23 Biocon India 200.3 30.5 43.5 1,838
24 Cubist Pharmaceuticals USA 194.7 57.4 (0.4) 746
25 Enzon Pharmaceuticals USA 185.7 43.5 21.3 722
26 QLT Canada 175.1 56.4 (101.6) 653
27 ViroPharma USA 167.2 19.2 66.7 651
28 Alkermes USA 166.6 89.1 3.8 617
29 Crucell Netherlands 165.3 84.9 (110.0) 611
30 United Therapeutics USA 159.6 57.6 74.0 585
31 LifeCell USA 141.7 16.5 20.5 573
32 Ligand Pharmaceuticals USA 141.0 41.9 (31.7) 540
33 Myriad Genetics USA 114.3 83.8 (38.2) 511
34 Exelixis USA 98.7 185.5 (101.5) 500
35 Cangene Canada 96.8 22.1 11.6 498
36 InterMune USA 90.8 103.8 (107.2) 492
37 Nabi Biopharmaceuticals USA 89.9 37.6 (58.7) 487
38 BioMarin Pharmaceutical USA 84.2 66.7 (28.5) 417
39 Lexicon Pharmaceuticals USA 72.8 106.7 (54.3) 410
40 Progenics Pharmaceuticals USA 69.9 61.7 (21.6) 410
41 Innogenetics Belgium 67.5 32.1 (31.5) 371
42 Idenix Pharmaceuticals USA 67.4 96.1 (75.1) 359
43 MorphoSys Germany 66.6 21.9 7.6 336
44 Omrix Biopharmaceuticals USA 63.8 3.4 23.1 335
45 Regeneron Pharmaceuticals USA 63.4 137.1 (102.3) 323
46 Acambis UK 57.0 68.2 (30.4) 285
47 Tanox USA 56.1 53.4 (2.6) 285
48 ViaCell USA 54.4 14.0 (21.0) 282
49 Indevus Pharmaceuticals USA 50.5 43.2 -50.6 279
50 Medarex USA 48.6 194.5 (181.7) 277
51 NPS Pharmaceuticals USA 48.5 68.4 (112.7) 276
52 Monogram Biosciences USA 48.0 19.0 (38.7) 274
53 Oscient Pharmaceuticals USA 46.2 12.4 (78.5) 267
54 Array BioPharma USA 45.0 33.4 (39.6) 263
55 AEterna Zentaris Canada 41.4 28.7 33.4 260
56 IsoTis Switzerland 40.7 7.7 (18.5) 255
57 Enzo Biochem USA 39.8 7.9 (15.7) 255
58 CuraGen USA 39.6 58.5 (59.8) 254
59 Neurocrine Biosciences USA 39.2 97.7 (107.2) 254
60 MediGene Germany 38.4 26.7 (8.7) 248
61 Life Therapeutics Australia 37.6 0.1 (31.2) 245
62 Inspire Pharmaceuticals USA 37.1 42.5 (42.1) 238
63 CV Therapeutics USA 36.8 135.3 (274.3) 233
64 Cerus USA 35.6 29.5 (4.8) 208
65 SciClone Pharmaceuticals USA 32.7 14.1 0.7 197
66 ImmunoGen USA 32.1 40.9 (17.8) 197
67 Protherics UK 30.9 11.8 (16.5) 196
68 Arena Pharmaceuticals USA 30.6 103.4 (88.3) 195
69 Vernalis UK 30.1 71.7 (78.2) 192
70 Bavarian Nordic Denmark 29.5 19.9 (27.1) 191
71 Xoma USA 29.5 52.1 (51.8) 189
72 GPC Biotech Germany 28.5 81.3 (80.4) 180
73 Micromet USA 27.6 28.3 0.0 171
74 Targacept USA 27.5 21.8 (1.2) 170
75 Carrington Laboratories USA 27.4 5.8 (7.6) 166
76 Acorda Therapeutics USA 27.4 12.1 (60.0) 158
77 Anika Therapeutics USA 26.8 3.6 4.6 156
78 Human Genome Sciences USA 25.8 209.2 (251.2) 151
79 Dusa Pharmaceuticals USA 25.6 6.2 (31.3) 150
80 ZymoGenetics USA 25.4 128.5 (130.0) 150
81 Maxygen USA 25.0 49.1 (16.5) 147
82 Isis Pharmaceuticals USA 24.5 80.6 (45.9) 133
83 Genmab Denmark 23.9 90.6 (77.4) 128
84 BioSciMed USA 23.9 11.6 (1.0) 126
85 Bioniche Life Sciences Canada 24.1 11.9 (1.0) 127
86 Vitrolife Sweden 23.2 3.3 2.1 124
87 Coley Pha
91 Medivir Group Sweden 18.8 39.7 (29.7) 88
92 Peptech Australia 18.7 4.6 3.8 85
93 Ambrilia Biopharma Canada 17.4 8.3 (2.1) 85
94 Cytogen USA 17.3 7.3 (15.1) 85
95 Cayman Chemical Company USA 16.2 3.3 0.4 148
96 Replidyne USA 16.0 38.3 (34.6) 79
97 Sinovac Biotech China 15.4 0.3 (0.7) 67
98 Trimeris USA 15.2 18.3 7.4 64
99 Avanir Pharmaceuticals USA 15.2 29.2 (62.6) 64
100 Adolor USA 15.1 56.7 (69.7) 51

References[edit]

  1. ^ "The Convention on Biological Diversity (Article 2. Use of Terms)." United Nations. 1992. Retrieved on February 6, 2008.
  2. ^ Top 25 Biotech Companies, Genetic Engineering & Biotechnology News, August 2012
  3. ^ Top 100 biotechnology companies, MedAdNews, June 2007
  4. ^ DePalma, Angelo (August 2005), "Twenty-Five Years of Biotech Trends", Genetic Engineering News (Mary Ann Liebert) 25 (14): 1, 14–23, ISSN 1935-472X, retrieved 2008-08-17 

External links[edit]