Shepard et al., 1974
It had also been associated with a number of diseases in humans, including nonspecific urethritis, infertility, chorioamnionitis, stillbirth, premature birth, and, in the perinatal period, pneumonia, bronchopulmonary dysplasia and meningitis. However, given the relatively low pathogenicity of the organism, its role in some of these diseases remains contentious.
The six recognised Ureaplasma species have a GC content of 27–30%, and a genome size ranging from 0.76 to 1.17 Mbase pairs, and cholesterol is required for growth.  A defining characteristic of the genus is that they perform urea hydrolysis. Some strains originally classified as U. urealyticum should be treated as a new species, U. parvum.
Doxycycline is the drug of choice, but azithromycin is also used as a five-day course rather than a single dose that would be used to treat Chlamydia infection; streptomycin is an alternative, but is less popular because it must be injected. Penicillins are ineffective — U. urealyticum does not have a cell wall, which is the drug's main target. 
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