Urethral syndrome

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Urethral syndrome
Classification and external resources
ICD-10 N34.3
ICD-9 597.81
eMedicine med/3081

Urethral syndrome is defined as symptoms suggestive of a lower urinary tract infection but in the absence of significant bacteriuria with a conventional pathogen.[1] There are other non-infective causes that should be considered such as trauma, allergies, anatomical features such as diverticula, and post-surgical scarring.

Contents

Presentation [edit]

Most women will give a history of chronic recurrent urinary tract infections (UTI) but the cultures seem to not show any conventional bacterial growth,[2] and pyuria (more than 5 white blood cells per High Power Field) is absent. There may also be a history of these episodes often being related to sexual intercourse.

Some physicians believe that urethral syndrome may be due to a low grade infection of the Skene's glands on the sides and bottom of the urethra.[citation needed] The Skene's glands are embryologically related to the prostate gland in the male, thus urethral syndrome may share a comparable etiology with chronic prostatitis.[citation needed]

Treatment [edit]

Treatment of acute urethral syndrome is antibiotics.[vague][citation needed] For chronic urethral syndrome, a long term, low dose antibiotic treatment is given on a continuous basis or after intercourse each time if intercourse appears to trigger symptoms.[citation needed]

As a hormonal imbalance may also be considered a source for urethral syndrome, hormone replacement therapy and oral contraceptive pill (birth-control pills) are also used to treat the symptoms of this condition.[3]

See also [edit]

References [edit]

  1. ^ Hamilton-Miller JM (May 1994). "The urethral syndrome and its management". J. Antimicrob. Chemother. 33. Suppl A: 63–73. PMID 7928838. 
  2. ^ Brumfitt W, Hamilton-Miller JM, Gillespie WA (July 1991). "The mysterious "urethral syndrome"". BMJ 303 (6793): 1–2. doi:10.1136/bmj.303.6793.1. PMC 1670265. PMID 1859947. 
  3. ^ "eMedicine - Urethral Syndrome : Article by Martha K Terris". Retrieved 2008-09-25.