Urtoxazumab

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Urtoxazumab ?
Monoclonal antibody
Type Whole antibody
Source Humanized (from mouse)
Target E. coli Shiga-like toxin II B subunit
Clinical data
Legal status
?
Identifiers
CAS number 502496-16-4 N
ATC code None
Chemical data
Formula C6414H9934N1718O2010S40 
Mol. mass 144.6 kDa
 N (what is this?)  (verify)

Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.[1][2]

References[edit]

  1. ^ International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
  2. ^ López, EL; Contrini, MM; Glatstein, E; González Ayala, S; Santoro, R; Allende, D; Ezcurra, G; Teplitz, E et al. (2009). "Safety and Pharmacokinetics of Urtoxazumab, a Humanized Monoclonal Antibody Against Shiga-Like Toxin 2 in Healthy Adults and Pediatric STEC- Infected Patients". Antimicrobial agents and chemotherapy 54 (1): 239–243. doi:10.1128/AAC.00343-09. PMC 2798559. PMID 19822704.