Vagina in the female human reproductive system.
Vulva with vaginal opening
|Artery||superior part to uterine artery, middle and inferior parts to vaginal artery|
|Vein||uterovaginal venous plexus, vaginal vein|
|Nerve||Sympathetic: lumbar splanchnic plexus
Parasympathetic: pelvic splanchnic plexus
|Lymph||upper part to internal iliac lymph nodes, lower part to superficial inguinal lymph nodes|
|Precursor||urogenital sinus and paramesonephric ducts|
The vagina is a fibromuscular elastic tubular tract (passage) which is a sex organ and mainly functions for the facilitation of sexual intercourse and childbirth. In mammals (especially primates), menstruation, which is the periodic discharge of blood and mucosal tissue from the inner lining of the uterus through the vagina, is another primary function of the vagina and usually signals fertility. The location and size of the vagina varies among species, and may vary in size within the same species. In humans, the vagina leads from the opening of the vulva to the uterus (womb), but the vaginal tract ends at the cervix.
Unlike mammalian males, who usually have only one genital orifice, mammalian females usually have two, the urethra and the vagina. The vaginal opening is much larger than the urethral opening, and both openings are protected by the labia. Regarding amphibians, birds, reptiles and monotremes, the female reproductive tract is generally known among zoologists as a cloaca; in these species, it may additionally serve as intestinal and urinary tracts.
The vagina plays a significant role in human female sexuality and sexual pleasure. During sexual arousal for humans and others animals, vaginal moisture increases by way of vaginal lubrication, to reduce friction and allow for smoother penetration of the vagina during sexual activity. In the absence or presence of sufficient vaginal lubrication, the texture of the vaginal walls can create friction for the penis during sexual intercourse and stimulate it toward ejaculation, enabling fertilization. In addition, a variety of sexually transmitted infections (STIs/STDs) and other disorders can affect the vagina. Because of the risk of STIs/STDs, health authorities, such as the World Health Organization (WHO), or other health outlets, recommend safe sex practices.
Cultural perceptions of the vagina have persisted throughout history; these perceptions range from viewing the vagina as the focus of sexual desire, a metaphor for life via birth, as an organ inferior to the penis, or as visually unappealing or otherwise vulgar.
- 1 Etymology and definition
- 2 Structure
- 3 Function
- 4 Clinical significance
- 5 Society and culture
- 6 Other animals
- 7 See also
- 8 References
- 9 External links
Etymology and definition
The term vagina is from Latin vāgīna, literally "sheath" or "scabbard." It is often referred to as the birth canal in the context of pregnancy and childbirth, though the term is, by definition, the area between the outside of the vagina and the fully dilated uterus.
The Latinate plural "vaginae" is rarely used in English. Colloquially, the word vagina is often used to refer to the vulva or to the female genitals in general. However, by its dictionary and anatomical definitions, vagina refers exclusively to the specific internal structure.
The vagina is derived from the embryonic Müllerian duct. During sexual differentiation (sex development of the differences between males and females), if exposed to testosterone, fusion of the urogenital folds (elongated spindle-shaped structures that contribute to the formation of the urethral groove on the belly aspect of the genital tubercle) allows the urogenital sinus to close completely and form the spongy urethra, while the labioscrotal swellings unite to form the scrotum. In the absence of testosterone, the urogenital sinus persists as the vestibule of the vagina, the two urogenital folds form the labia minora, and the labioscrotal swellings enlarge to form the labia majora.
General structure and histology
The human vagina is an elastic muscular canal that extends from the cervix (or uterine cavity) to the vulva. It, along with the inside of the vulva, is reddish pink in color, and it connects the superficial vulva to the cervix of the deep uterus. The vagina is posterior to the urethra and bladder, and reaches across the perineum superiorly and posteriorly toward the cervix; at approximately a 90 degree angle, the cervix protrudes into the vagina.
The vagina's internal lining consists of stratified squamous epithelium. Beneath this lining is a smooth muscle layer, which may contract during vaginal intercourse and when giving birth. Beneath the muscle is a connective tissue layer called adventitia.
Maternal estrogen, from birth to 10-14 days, is the reason newborn females have a stratified squamous epithelium. After this age range, through to the prepubertal age and in the post-menopause age, the epithelium thins out and is composed of a few layers. The epithelium is absent of glands, from puberty up until menopause. Consisting of three different layers of cells – superficial cornified cells, intermediate cells and basal cells – estrogen supplies the intermediate and superficial cells with glycogen. The cells layering the vaginal area of the cervix become stable with the intermediate and superficial cells, and the intermediate and superficial cells reach to the squamocolumnar junction (the area of the cervix where the columnar epithelium takes the place of the uterus squamous lining of the vagina) at the external orifice of the uterus (external os). The superficial cells exfoliate continuously, especially while in an inflammatory or neoplastic (tumorous) state. The basal cells replace the superficial cells, and keratinization results when the epithelium is exposed to the dry external atmosphere.
For blood and nerve supply, relevant arteries are the cervicovaginal (the uterine cervix and the vagina) branch of the uterine artery, the vaginal artery, middle rectal artery, and the internal pudendal artery. The veins are connected by anastomosis (the connection of separate parts of a branching system to form a network), resulting in the formation of the anterior and posterior azygos (unpaired) arteries. The nerve supply of the vagina is provided by the sympathetic and parasympathetic areas of the pelvic plexus, with the pudendal nerve supplying the lower area.
Regions and layers
Where the vaginal lumen surrounds the cervix of the uterus, it is divided into four regions of fornices (the vaginal fornix); these are the anterior, posterior, and the right lateral and left lateral (the lateral fornix). The posterior is deeper and the anterior is shallow. While the anterior and posterior walls are placed together, the lateral walls, especially their middle area, are relatively more rigid; because of this, they have an H-shape across the section.
Supporting the vagina are its upper third, middle third and lower third. The upper third concerns the levator ani muscles (transcervical, pubocervical) and the sacrocervical ligaments; these areas are also described as the cardinal ligaments laterally and uterosacral ligaments posterolaterally. The middle third of the vagina concerns the urogenital diaphragm (also described as the paracolpos and pelvic diaphragm). The lower third concerns the perineal body; it is sometimes described as containing the perineal body, pelvic diaphragm and urogenital diaphragm.
- the first layer is made up of a stratified squamous non-keratinized epithelium and is an underlying lamina propria of connective tissue (a layer of connective tissue that is highly vascular under the base area lining the epithelium)
- the second layer is the muscular layer, which is composed of smooth muscle fibers and situated longitudinally and circularly
- the third layer is the adventitia, which is a dense connective tissue that blends with the fascia surrounding the area
- the first layer is an inner layer of non-keratinized squamous epithelium, which forms the folds or rugae and facilitate the vagina's ability to expand large enough for child birth. The rugae are a series of ridges produced by folding of the wall of the outer third of the vagina; they are transverse epithelial ridges and their function is to provide the vagina with increased surface area for extension and stretching
- the second layer of the vagina is connective tissue, which contains blood vessels
- the third layer is the muscle layer; it is an outer layer of longitudinal muscle, as well as the inner layer of circular muscle
- the fourth layer is an outer layer of connective tissue; it is continuous with the other pelvic organs and is made up of blood and lymphatic vessels and fibers
The upper one-fourth of the vagina is separated from the rectum by the recto-uterine pouch. Above the vagina is a cushion of fat called the mons pubis which surrounds the pubic bone and provides protective support during vaginal intercourse.
Vaginal opening and hymen
The vaginal opening (or orifice) is at the caudal end of the vulva, behind the opening of the urethra, resting at the posterior end of the vestibule. It is closed by the labia minora in female virgins and in females who have never given birth (nulliparae), but may be exposed in females who have given birth (parous females).
The hymen is a membrane of tissue that surrounds or partially covers the vaginal opening. The effects of vaginal intercourse and childbirth on the hymen are variable. If the hymen is sufficiently elastic, it may return to nearly its original condition. In other cases, there may be remnants (carunculae myrtiformes), or it may appear completely absent after repeated penetration. Additionally, the hymen may be lacerated by disease, injury, medical examination, masturbation or physical exercise. For these reasons, it is not possible to definitively determine whether or not a girl or woman is a virgin by examining her hymen.
The Bartholin's glands, located near the vaginal opening and cervix, were originally thought to be the primary source for vaginal lubrication, but they provide only a few drops of mucus for vaginal lubrication; the significant majority of vaginal lubrication is generally believed to be provided by plasma seepage from the vaginal walls, which is called vaginal transudation. Vaginal transudation, which initially forms as sweat-like droplets, is caused by vascular engorgement of the vagina (vasocongestion); this results in the pressure inside the capillaries increasing the transudation of plasma through the vaginal epithelium.
Before and during ovulation, the cervix's mucus glands secrete different variations of mucus, which provides an alkaline environment in the vaginal canal that is favorable to the survival of sperm. "Vaginal lubrication typically decreases as women age, but this is a natural physical change that does not normally mean there is any physical or psychological problem. After menopause, the body produces less estrogen, which, unless compensated for with estrogen replacement therapy, causes the vaginal walls to thin out significantly."
Variations and size
In its normal state, there is anatomical variation in the length of the vagina of a woman of child-bearing age. The length is approximately 7.5 cm (2.5 to 3 in) across the anterior wall (front), and 9 cm (3.5 in) long across the posterior wall (rear), making the posterior fornix deeper than the anterior. During sexual arousal, the vagina expands in both length and width.
The vagina provides a path for menstrual blood and tissue to leave the body. In industrial societies, tampons, menstrual cups and sanitary napkins may be used to absorb or capture these fluids. Vaginal secretions are primarily from the uterus, cervix, and transudation of the vaginal epithelium in addition to miniscule lubrication from the Bartholin's glands upon sexual arousal. It takes little vaginal secretion to make the vagina moist. The secretions may be minor in excess during sexual arousal, the middle of the menstrual cycle, a little prior to menstruation, or during pregnancy.
The concentration of the nerve endings that lie close to the entrance of a woman's vagina (the lower third) can provide pleasurable vaginal sensations during sexual activity when stimulated, and many women additionally derive pleasure from a feeling of closeness and fullness during penetration of the vagina. The vagina as a whole, however, lacks nerve endings, which commonly hinders a woman's ability to receive sufficient sexual stimulation, including orgasm, solely from vaginal sexual activity. The outer one-third of the vagina, especially near the opening, contains the majority of the vaginal nerve endings, making it more sensitive to touch than the inner two-thirds of the vaginal barrel. This factor is considered to make the process of child birth significantly less painful, because an increased number of nerve endings means that there is an increased possibility for pain as well as pleasure.
There are a variety of ways that pleasure can be received from vaginal stimulation in addition to penile penetration, including by masturbation, fingering, oral sex (cunnilingus), or by specific sex positions (such as the missionary position or the spoons sex position). Some women use sex toys, such as a vibrator or dildo, for vaginal pleasure. Foreplay is often used to incite sexual arousal, and may include one or more of the aforementioned sexual activities. The clitoris additionally plays a part in vaginal stimulation, as it is a sex organ of multiplanar structure containing an abundance of nerve endings, with a broad attachment to the pubic arch and extensive supporting tissue to the mons pubis and labia; it is centrally attached to the urethra, and research indicates that it forms a tissue cluster with the vagina. This tissue is perhaps more extensive in some women than in others, which may contribute to orgasms experienced vaginally.
During sexual arousal, and particularly the stimulation of the clitoris, the walls of the vagina lubricate. This reduces friction or injury that can be caused by insertion of the penis into the vagina or other penetration of the vagina during sexual activity. With sexual arousal, the human vagina lengthens rapidly, to an average of about 4 in.(10 cm), but can continue to lengthen in response to pressure. As the woman becomes fully aroused, the vagina tents (last ²⁄₃) expands in length and width, while the cervix retracts. The elastic walls of the vagina stretch or contract, with support from the pelvic muscles, to the size of the inserted penis or other object, stimulating the penis and helping to cause the male to experience orgasm and ejaculation; this in turn enables fertilization.
An area in the vagina that may be an erogenous zone is the G-spot (also known as the Gräfenberg spot); it is typically defined as being located at the anterior wall of the vagina, about five centimeters in from the entrance. Some women experience intense pleasure, and sometimes an orgasm, if this area is stimulated during sexual activity. A G-spot orgasm may be responsible for female ejaculation, leading some doctors and researchers to believe that G-spot pleasure comes from the Skene's glands, a female homologue of the prostate, rather than any particular spot on the vaginal wall. Other researchers consider the connection between the Skene's glands and the G-spot to be weak. They contend that the Skene's glands do not appear to have receptors for touch stimulation, and that there is no direct evidence for their involvement. The G-spot's existence, and existence as a distinct structure, is still under dispute, as its location can vary from woman to woman, appears to be nonexistent in some women, and it is hypothesized to be an extension of the clitoris and therefore the reason for orgasms experienced vaginally.
During childbirth, the vagina provides the channel to deliver the newborn from the uterus to its independent life outside the body of the mother. During birth, the elasticity of the vagina allows it to stretch to many times its normal diameter.
Vaginal ecosystem and acidity
The vagina is a nutrient rich environment that harbors a unique and complex microflora. It is a dynamic ecosystem that undergoes long term changes, from neonate to puberty and from the reproductive period (menarche) to menopause. Moreover, under the influence of hormones, such as estrogen (estradiol), progesterone and follicle stimulating hormone (FSH), the vaginal ecosystem undergoes cyclic or periodic changes, i.e. during menses and pregnancy. One significant variable parameter is the vaginal pH, which varies significantly during a woman‘s lifespan, from 7.0 in premenarchal girls, to 3.8-4.4 in women of reproductive age to 6.5-7.0 during menopause without hormone therapy and 4.5-5.0 with hormone replacement therapy. Estrogen, glycogen and lactobacilli are important factors in this variation.
The vagina is self-cleansing and therefore usually needs no special treatment. Doctors generally discourage the practice of douching. Since a healthy vagina is colonized by a mutually symbiotic flora of microorganisms that protect its host from disease-causing microbes, any attempt to upset this balance may cause many undesirable outcomes, including but not limited to abnormal discharge and yeast infection.
The vagina is examined during gynecological exams, often using a speculum, which holds the vagina open for visual inspection of the cervix or taking of samples (see pap smear). Medical activities involving the vagina, including examinations, administration of medicine, and inspection of discharges, are also referred to as being per vaginam (or p.v.).
The healthy vagina of a woman of child-bearing age is acidic, with a pH normally ranging between 3.8 and 4.5. This is due to the degradation of glycogen to the lactic acid by enzymes secreted by the Döderlein's bacillus. This is a normal commensal of the vagina. The acidity retards the growth of many strains of pathogenic microbes.
Intravaginal administration is a route of administration where the substance is applied to the inside of the vagina. Pharmacologically, it has the potential advantage to result in effects primarily in the vagina or nearby structures (such as the vaginal portion of cervix) with limited systemic adverse effects compared to other routes of administration.
Sexually transmitted infections and other disorders
The herpes simplex virus (HSV), which can be transmitted sexually, can infect the vulva, vagina, and cervix, and this may result in small, painful, recurring blisters and ulcers. It is also common for there to be an absence of any noticeable symptoms. Other sexually transmitted infections (STIs/STDs) that may infect the vagina include gonorrhea, chlamydia, trichomoniasis and human papillomavirus (HPV), which may cause genital warts. HIV/AIDS can be contracted through the vagina during vaginal intercourse, but it is not associated with any local vaginal or vulval disease. Health authorities and other health outlets recommend safe sex practices when engaging in sexual activity.
Vaginismus, which is not the same thing as vaginitis (an inflammation of the vagina), is an involuntary tightening of the vagina due to a conditioned reflex of the muscles in the area during vaginal penetration. It can affect any form of vaginal penetration, including sexual intercourse, insertion of tampons and menstrual cups, and the penetration involved in gynecological examinations. Various psychological and physical treatments are possible to help alleviate it.
With regard to other vaginal health issues, an increased pH of the vagina (with a commonly used cut-off of pH 4.5 or higher) can be caused by bacterial overgrowth, as occurs in bacterial vaginosis and trichomoniasis, or rupture of membranes in pregnancy. Vaginal cancer is very rare, but its symptoms include abnormal vaginal bleeding or vaginal discharge. Vaginal prolapse may result in the case of weakened pelvic muscles, which is a common result of childbirth; in the case of this prolapse, the rectum, uterus, or bladder pushes on the vagina, and severe cases result in the vagina protruding out of the body. Kegel exercises have been used to strengthen the pelvic floor, and may help prevent or remedy vaginal prolapse.
In the case of oral sex, a fatal condition known as an air embolism, in which an air bubble travels throughout the bloodstream and can obstruct the vessel, can result if air is blown into a pregnant woman's vagina during cunnilingus; this is because pregnant women have an increased vascularity of the vagina and uterus, and an air embolism can force air into the uterine veins.
Another vaginal disorder is persistent genital arousal disorder (PGAD), which results in a spontaneous, persistent, and uncontrollable genital arousal, with or without orgasm, unrelated to any feelings of sexual desire. Because PGAD is relatively rare and, as its own concept apart from clitoral priapism (a rare, potentially painful medical condition in which, for an unusually extended period of time, the erect clitoris does not return to its relaxed state), has only been researched since 2001, there is little research into what may cure or remedy the disorder. In some recorded cases, PGAD was caused by, or caused, a pelvic arterial-venous malformation with arterial branches to the clitoris; surgical treatment was effective in these cases.
The presence of unusual lumps in the wall or base of the vagina is always abnormal. The most common of these is Bartholin's cyst. The cyst, which can feel like a pea, is formed by a blockage in glands which normally supply the opening of the vagina. This condition is easily treated with minor surgery or silver nitrate. Other less common causes of small lumps or vesicles are herpes simplex. They are usually multiple and very painful with a clear fluid leaving a crust. They may be associated with generalized swelling and are very tender. Lumps associated with cancer of the vaginal wall are very rare and the average age of onset is seventy years. The most common form is squamous cell carcinoma, then cancer of the glands or adenocarcinoma and finally, and even more rarely, melanoma.
Most vaginal discharges occur due to normal bodily functions such as menstruation or sexual arousal (vaginal lubrication). Abnormal discharges, however, can indicate disease.
Normal vaginal discharges include blood or menses (from the uterus), the most common, and clear fluid either as a result of sexual arousal or secretions from the cervix. Other non-infective causes include dermatitis. Non-sexually transmitted discharges occur from bacterial vaginosis and thrush or candidiasis. The final group of discharges include the sexually transmitted diseases gonorrhea, chlamydia, and trichomoniasis. The discharge from thrush is slightly pungent and white, that from trichomoniasis more foul and greenish, and that from foreign bodies resembling the discharge of gonorrhea, greyish or yellow and purulent (pus-like).
All sores involve a breakdown in the walls of the fine membrane of the vaginal wall. The most common of these are abrasions and small ulcers caused by trauma. While these can be inflicted during rape most are actually caused by excessive rubbing from clothing or improper insertion of a sanitary tampon. The typical ulcer or sore caused by syphilis is painless with raised edges. These are often undetected because they occur mostly inside the vagina. The sores of herpes which occur with vesicles are extremely tender and may cause such swelling that passing urine is difficult. In the developing world, a group of parasitic diseases also cause vaginal ulceration, such as leishmaniasis, but these are rarely encountered in the west. All of the aforementioned local vulvovaginal diseases are easily treated. Often, only shame prevents patients from presenting for treatment.
The vagina may be an aspect of genital modification during vaginoplasty or labiaplasty; for example, alteration to the inner labia (also known as the vaginal lips or labia minora). There are two main categories of women seeking cosmetic genital surgery: those with congenital conditions such as an intersex condition, and those with no underlying condition who experience physical discomfort or wish to alter the appearance of their genitals because they believe they do not fall within a normal range.
Female genital mutilation (FGM), another aspect of female genital modification, may additionally be known as female circumcision or female genital cutting (FGC). The most severe form of FGM is infibulation, in which there is removal of all or part of the inner and outer labia (labia minora and labia majora) and the closure of the vagina; this is called Type III FGM, and it involves a small hole being left for the passage of urine and menstrual blood, with the vagina being opened up for sexual intercourse and childbirth.
Society and culture
Biological perceptions, symbolism and vulgarity
There have been various perceptions of the vagina throughout history, ranging from it being the center of sexual desire, a symbol of sexual power, a metaphor for life via birth, inferior to the penis, visually unappealing or inherently "smelly," or otherwise vulgar. In Ancient times, it was often considered equivalent (homologous) to the penis; anatomists Galen (129 AD – 200 AD) and Vesalius (1514–1564), regarded the organs as structurally the same, except for the vagina being inverted. Anatomical studies over latter centuries, however, showed the clitoris to be the penile equivalent.
The release of vaginal fluids were considered by medical practitioners to cure or remedy a number of ailments; various methods were used over the centuries to release "female seed" (via vaginal lubrication or female ejaculation) as a treatment for suffocation ex semine retento (suffocation of the womb), female hysteria or green sickness. Methods included a midwife rubbing the walls of the vagina or insertion of the penis or penis-shaped objects into the vagina. Supposed symptoms of female hysteria included faintness, nervousness, insomnia, fluid retention, heaviness in abdomen, muscle spasm, shortness of breath, irritability, loss of appetite for food or sex, and "a tendency to cause trouble". Women considered suffering from the condition would sometimes undergo "pelvic massage" — stimulation of the genitals by the doctor until the woman experienced "hysterical paroxysm" (i.e., orgasm). Paroxysm was regarded as a medical treatment, and not a sexual release. The categorization of female hysteria has ceased to be recognized as a medical condition since the 1920s.
The vagina has been termed many vulgar names, two being cunt and pussy. Cunt is used as a derogatory epithet referring to people of either sex. This usage is relatively recent, dating from the late nineteenth century. Reflecting different national usages, cunt is described as "an unpleasant or stupid person" in the Compact Oxford English Dictionary, whereas Merriam-Webster has a usage of the term as "usually disparaging and obscene: woman", noting that it is used in the U.S. as "an offensive way to refer to a woman"; and the Macquarie Dictionary of Australian English states that it is "a despicable man". When used with a positive qualifier (good, funny, clever, etc.) in Britain, New Zealand and Australia, it can convey a positive sense of the object or person referred to. Pussy, on the other hand, can indicate "cowardice or weakness", and "the human vulva or vagina" or by extension "sexual intercourse with a woman".
In contemporary art and literature
The Vagina Monologues, a 1996 episodic play by Eve Ensler, has been noted for its success in making female sexuality a topic of public discourse. It is made up of a varying number of monologues read by a number of women. Initially, Ensler performed every monologue herself, with subsequent performances featuring three actresses; latter versions feature a different actress for every role. Each of the monologues deals with an aspect of the feminine experience, touching on matters such as sexual activity, love, rape, menstruation, female genital mutilation, masturbation, birth, orgasm, the various common names for the vagina, or simply as a physical aspect of the body. A recurring theme throughout the pieces is the vagina as a tool of female empowerment, and the ultimate embodiment of individuality.
Reasons for vaginal modification
With the exception of voluntary vaginoplasty or labiaplasty, modification of the vagina is generally a matter of FGM. Significant controversy surrounds FGM, with the World Health Organization (WHO) being one of many health organizations that have campaigned against the procedures on behalf of human rights, stating that "FGM has no health benefits" and that it is "a violation of the human rights of girls and women" and "reflects deep-rooted inequality between the sexes". The practice has existed at one point or another in almost all human civilizations, most commonly to exert control over the sexual behavior, including masturbation, of girls and women. Custom and tradition are the most frequently cited reasons for FGM, with some cultures believing that not performing it has the possibility of disrupting the cohesiveness of their social and political systems, such as FGM also being a part of a girl's initiation into adulthood. Often, a girl is not considered an adult in a FGM-practicing society unless she has undergone FGM.
FGM is carried out in several countries, especially in Africa, and to a lesser extent in other parts of the Middle East and Southeast Asia, on girls from a few days old to mid-adolescent, often to reduce sexual desire in an effort to preserve vaginal virginity. It may also be that FGM was "practiced in ancient Egypt as a sign of distinction among the aristocracy"; there are reports that traces of infibulation are on Egyptian mummies.
The vagina (along with the penis) is a general feature of animals in which the female is internally fertilised (other than by traumatic insemination). The shape of the vagina varies among different animals.
In placental mammals and marsupials, the vagina leads from the uterus to the exterior of the female body. Female marsupials have two lateral vaginas, which lead to separate uteri, but both open externally through the same orifice. The urethra and vagina of the female spotted hyena exits through the clitoris, allowing the females to urinate, copulate and give birth through the clitoris.
In birds, monotremes, and some reptiles, a homologous part of the oviduct leads from the shell gland to the cloaca. In some jawless fish, there is neither oviduct nor vagina and instead the egg travels directly through the body cavity (and is fertilised externally as in most fish and amphibians). In insects and other invertebrates, the vagina can be a part of the oviduct (see insect reproductive system).
In 2014, the scientific journal Current Biology reported that four species of Brazilian insects in the genus Neotrogla were found to have sex-reversed genitalia. The male insects of those species have vagina-like openings, while the females have penis-like organs.
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