Vesicular monoamine transporter 1

solute carrier family 18 (vesicular monoamine), member 1
Identifiers
Symbol	SLC18A1
Alt. symbols	VMAT1, VAT1
Entrez	6570
HUGO	10934
OMIM	193002
RefSeq	NM_003053
UniProt	P54219
Other data
Locus	Chr. 8 p21.3

VMAT1 (Vesicular monoamine transporter 1) is a protein that transports the monoamines into intracellular vesicles.

In chromaffin cells, it is responsible for transporting newly synthesized epinephrine from the cytosol back into chromaffin granules in preparation for release.

For norepinephrine to be acted upon by PNMT in the cytosol, it must first be shipped out of granules of the chromaffin cells. This may occur via the catecholamine-H+ exchanger VMAT1.

External links

• MeSH Vesicular+Monoamine+Transporter+1