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Systematic (IUPAC) name
Clinical data
869497-75-6 YesY
PubChem CID 10446295
IUPHAR ligand 1277
Chemical data
Formula C13H15ClN4O
278.737 g/mol
 YesY (what is this?)  (verify)

VUF-6002 (JNJ 10191584) is a drug which acts as a potent and selective antagonist at the histamine H4 receptor.[1] It has antiinflammatory and analgesic effects in animal studies of acute inflammation.[2]


  1. ^ Zhang, M; Thurmond, RL; Dunford, PJ (2007). "The histamine H(4) receptor: a novel modulator of inflammatory and immune disorders". Pharmacology & therapeutics 113 (3): 594–606. doi:10.1016/j.pharmthera.2006.11.008. PMID 17275092. 
  2. ^ Coruzzi, G; Adami, M; Guaita, E; De Esch, IJ; Leurs, R (2007). "Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation". European Journal of Pharmacology 563 (1–3): 240–4. doi:10.1016/j.ejphar.2007.02.026. PMID 17382315.