Valine—3-methyl-2-oxovalerate transaminase

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valine-3-methyl-2-oxovalerate transaminase
Identifiers
EC number 2.6.1.32
CAS number 9023-14-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a valine-3-methyl-2-oxovalerate transaminase (EC 2.6.1.32) is an enzyme that catalyzes the chemical reaction

L-valine + (S)-3-methyl-2-oxopentanoate \rightleftharpoons 3-methyl-2-oxobutanoate + L-isoleucine

Thus, the two substrates of this enzyme are L-valine and (S)-3-methyl-2-oxopentanoate, whereas its two products are 3-methyl-2-oxobutanoate and L-isoleucine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase. Other names in common use include valine-isoleucine transaminase, valine-3-methyl-2-oxovalerate aminotransferase, alanine-valine transaminase, valine-2-keto-methylvalerate aminotransferase, and valine-isoleucine aminotransferase.[citation needed]

References[edit]

  • Kagan, Z. S.; A. S. Dronov and V. L. Kretovich (1968). "[Some properties of valine-isoleucine- and valine-glutamate-aminotransferases of pea sprouts]". Doklady Akademii Nauk SSSR (in Russian) 179: 1236–1239.