Struve authored around 400 scientific works in his lifetime. He along with Boris Turaev worked on the Moscow Mathematical Papyrus and published its translation in 1930. As an Egyptologist he translated and published numerous Demotic documents from fonds of museums of the USSR. But his scientific research field was not limited to Egyptology. His major scientific works were also on the history and history of arts of Sumer, Babylonia, Assyria, Hittite Empire and other civilizations of the Ancient Near East. He authored numerous research papers and textbooks in these fields, including the generalizing work "History of Ancient East" (1941). Struve was the head of a large research team that began work on the publication of all Greek inscriptions from the Ancient Bosporan Kingdom. He also published a work on the history of the Ancient Northern Black Sea Coast, Caucasus and Middle Asia civilizations.