Veratrum album

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White Hellebore
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Monocots
Order: Liliales
Family: Melanthiaceae
Genus: Veratrum
Species: V. album
Binomial name
Veratrum album
L.

Veratrum album, commonly known as the False Helleborine (also known as White Hellebore, European White Hellebore, White Veratrum; syn. Veratrum lobelianum Bernh.[1]), is a medicinal plant[2][3] of the Liliaceae (lily family) or Melanthiaceae which is native to Europe.

Contents

[edit] Plant description

The plant is a perennial herb with a stout vertical rhizome covered with remnants of old leaf sheaths. The stems are stout, simple, 50 to 175 cm tall. They have been mistaken for yellow gentian, Gentiana lutea, which is used in beverages, resulting in poisoning.[4][5][6]

Resveratrol has been isolated from it.[7]

[edit] Uses

The root is very poisonous, with a paralyzing effect on the nervous system.[1] In two cases of fatal poisoning from eating the seeds, the toxins veratridine and cevadine were present in the blood at 0.17–0.40 nanograms/milliliter and 0.32–0.48 nanograms/milliliter, respectively. In 1983 sneezing powders produced from the herb in West Germany were reported to have caused severe intoxications in Scandinavia.[8]

[edit] History

In antiquity, an effective emetic based on white hellebore and a bitter oval seed (which Hahneman believed was the seed of erigeron or senecio) was mixed by the physicians of Antikyra, a city of Phokis in Greece.[9]

Leaves
Flower
Seeds

[edit] References

  1. ^ a b Veratrum album at Plants For A Future
  2. ^ Felter, Harvey Wickes. (1922) The Eclectic Materia Medica, Pharmacology and Therapeutics.
  3. ^ Felter, Harvey Wickes; Lloyd, John Uri. (1898) King's American Dispensatory.
  4. ^ Zagler, B.; Zelger, A.; Salvatore, C.; Pechlaner, C.; De Giorgi, F.; Wiedermann, C. (2005). "Dietary poisoning with Veratrum album--a report of two cases". Wiener klinische Wochenschrift 117 (3): 106–108. doi:10.1007/s00508-004-0291-x. PMID 15773425.  edit
  5. ^ Rauber-Lüthy, C.; Halbsguth, U.; Kupferschmidt, H.; König, N.; Mégevand, C.; Zihlmann, K.; Ceschi, A. (2010). "Low-dose exposure to Veratrum album in children causes mild effects--a case series". Clinical toxicology (Philadelphia, Pa.) 48 (3): 234–237. doi:10.3109/15563650903575243. PMID 20170391.  edit
  6. ^ Verovnik F. Naključna zastrupitev z belo čmeriko = Accidental poissoning with White hellebore. Zdravniški vestnik. 68(3); 1999: 157-160.
  7. ^ Resveratrol as a Chemopreventive Agent: A Promising Molecule for Fighting Cancer. Dominique Delmas, Allan Lançon, Didier Colin, Brigitte Jannin and Norbert Latruffe, Current Drug Targets, 2006, Vol. 7, No. 3 [1]
  8. ^ Fogh, A.; Kulling, P.; Wickstrom, E. (1983). "Veratrum alkaloids in sneezing-powder a potential danger". Journal of toxicology. Clinical toxicology 20 (2): 175–179. doi:10.3109/15563658308990062. PMID 6887310.  edit
  9. ^ Hahnemann, Samuel (1852), "A Medical Historical Dissertation on the Helleborism of the Ancients", The Lesser writings of Samuel Hahnemann, William Radde, p. 604, para. 117, http://books.google.co.uk/books?id=YwTZzl_fk74C 

[edit] External links

Media related to Veratrum album at Wikimedia Commons


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