Anthelmintic

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Anthelmintic effect of papain on Heligmosomoides bakeri.

Anthelminticsa or antihelminthics are drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill).

Pharmaceuticals[edit]

Anthelmintic resistance[edit]

The ability of parasites to survive treatments that are generally effective at the recommended dose rate is a major threat to the future control of worm parasites in small ruminants and horses. This is especially true of nematodes, and has helped spur development of aminoacetonitrile derivatives for treatment against drug resistant nematodes.

The clinical definition of resistance is a 95% or less reduction in a "Fecal Egg Count" test.[clarification needed]

Treatment with an antihelminthic drug kills worms whose phenotype renders them susceptible to the drug. But resistant parasites survive and pass on their "resistance" genes. Resistant varieties accumulate and finally treatment failure occurs. See drug resistance.

See also[edit]

References[edit]

Footnotes[edit]

General references[edit]

  • Department of the Army Headquarters (2004). U.S. Army Survival Manual Fm 21–76. Barnes & Noble Inc. ISBN 0-7607-4988-4. 

External links[edit]