Vesicle-associated membrane protein
From Wikipedia, the free encyclopedia
Vesicle associated membrane proteins (VAMP) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion.
- VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
- VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis.
- VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures.
- VAMP7 is found both in secretory granules and endosomes.
- VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.
- VAMP4 is involved in transport from the Golgi.[1]
[edit] References
- ^ Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH (1999). "Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking". Mol. Biol. Cell 10 (6): 1957–72. PMC 25394. PMID 10359608. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=25394.
[edit] External links
|
|
|
| Synaptic vesicle |
|
|
|
|
SNAP25 · SNAP29
Syntaxin (STX1A, STX1B, STX2, STX3, STX4, STX5, STX6, STX7, STX8, STX10, STX11, STX12, STX16, STX17, STX18, STX19)
Munc-18: STXBP1 · STXBP2 · STXBP3 · STXBP4 · STXBP5 · STXBP6
|
|
|
|
|
|
|
|
|
|
|
|
Other
|
|
|
|
| COPI |
|
|
| COPII |
|
|
| RME/Clathrin |
|
|
| Caveolae |
|
|
| Other/ungrouped |
|
|
|
|
|
