Vesiculo-vacuolar organelle
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A vesiculo-vacuolar organelle is an organelle found in the cytoplasm of endothelial cells that line both tumor and normal blood vessels.
They help actively transport fluid and cells across endothelial cells, contributing to the increase in vascular permeability that occurs during the process of inflammation. This kind of transport is mediated by VEGF, one of the chemical mediators of inflammation.
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