Vinca alkaloids are a set of anti-mitotic and anti-microtubule agents that were originally derived from the Periwinkle plant Catharanthus roseus.
Vinca alkaloids are used in the treatment of cancer. They are a class of cell-cycle-specific cytotoxic drugs that work by inhibiting the ability of cancer cells to divide: Acting upon tubulin, they prevent it from forming into microtubules, a necessary component for cellular division.
- Takimoto, C. H.; Calvo, E. (2008). "Chapter 3: Principles of Oncologic Pharmacotherapy". In Pazdur, R.; Wagman, L. D.; Camphausen, K. A.; Hoskins, W. J. Cancer Management: A Multidisciplinary Approach (11th ed.). ISBN 978-1-891483-62-2.
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