A music video for "Virtual Diva" was produced and filmed in Buenos Aires, Argentina. Around the end of January 2009, after celebrating with fellow working bachata group Marcy Place while performing at the Providence Club in New York, Don Omar was finishing up on recording his new studio album. It would eventually be announced that he would be traveling down to Argentina once again to start filming the music video, which finished production on February 13, 2009. The video feature Argentinean model Ingrid Grudke, who portrays a doctor who wants to perform a grand experiment transforming Don Omar into half-man, half-machine.
The song was also performed live for the first time on the MTV Tr3́svariety series, Entertainment as a Second Language, on February 26, 2009.