Vitamin D and Omega-3 Trial

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Vitamin D and Omega-3 Trial (VITAL) (VITamin D and OmegA-3 TriaL) is a 5 year trial to run from 2010 to determine the benefits of vitamin D and Omega-3 supplements on elderly Americans.[1] [2]

It aims to enroll 20,000 participants (women 55 or over, men 50 or over)[3][4] who will be randomized to one of four groups:[2]

  • daily vitamin D (2000 IU) and fish oil (1 g);
  • daily vitamin D and fish-oil placebo;
  • daily vitamin-D placebo and fish oil;
  • daily vitamin-D placebo and fish-oil placebo.

Participants will answer annual questionnaires[2] to determine effects on risk of cancer, heart disease, stroke, osteoporosis, diabetes, memory loss and depression.

References[edit]

  1. ^ http://www.medscape.com/viewarticle/705079 "Massive Vitamin-D/Omega-3 Trial for CVD, Cancer Prevention"
  2. ^ a b c http://www.vitalstudy.org/
  3. ^ Manson, JE.; Bassuk, SS.; Lee, IM.; Cook, NR.; Albert, MA.; Gordon, D.; Zaharris, E.; Macfadyen, JG. et al. (Jan 2012). "The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease". Contemp Clin Trials 33 (1): 159–71. doi:10.1016/j.cct.2011.09.009. PMC 3253961. PMID 21986389. 
  4. ^ http://www.vitalstudy.org/QA.html#eligible Retrieved April 5, 2013