WAY-161503

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WAY-161503
WAY-161503.svg
Identifiers
CAS number 276694-95-2 YesY
Properties
Molecular formula C11H11Cl2N3O
Molar mass 272.13 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

WAY-161503 is a full agonist at the serotonin 5-HT2B and 5-HT2C receptors. Administration of WAY-161503 decreased food intake in rats, an effect mediated by its action on the 5-HT2C receptors. In addition, there was no development of tolerance with up to 15 days of treatment. However, clinical utility of WAY-161,503 may be limited as activation of the 5-HT2B receptor has been linked to pulmonary hypertension and cardiac valve problems.[1]

References[edit]

  1. ^ Rosenzweig-Lipson, Sharon (February 2006). "Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503". Brain Research. 1073-1074: 240–251. doi:10.1016/j.brainres.2005.12.052. PMID 16430874.