WDR36

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WD repeat domain 36
Identifiers
Symbols WDR36 ; GLC1G; TA-WDRP; TAWDRP; UTP21
External IDs OMIM609669 HomoloGene6536 GeneCards: WDR36 Gene
RNA expression pattern
PBB GE WDR36 gnf1h08539 at tn.png
PBB GE WDR36 gnf1h08540 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 134430 225348
Ensembl ENSG00000134987 ENSMUSG00000038299
UniProt Q8NI36 Q3TA68
RefSeq (mRNA) NM_139281 NM_001110015
RefSeq (protein) NP_644810 NP_001103485
Location (UCSC) Chr 5:
110.43 – 110.47 Mb
Chr 18:
32.84 – 32.87 Mb
PubMed search [1] [2]

WD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene.[1][2][3]

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).[3]

References[edit]

  1. ^ Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ (Dec 2004). "The small-subunit processome is a ribosome assembly intermediate". Eukaryot Cell 3 (6): 1619–26. doi:10.1128/EC.3.6.1619-1626.2004. PMC 539036. PMID 15590835. 
  2. ^ Monemi S, Spaeth G, DaSilva A, Popinchalk S, Ilitchev E, Liebmann J, Ritch R, Heon E, Crick RP, Child A, Sarfarazi M (Mar 2005). "Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1". Hum Mol Genet 14 (6): 725–33. doi:10.1093/hmg/ddi068. PMID 15677485. 
  3. ^ a b "Entrez Gene: WDR36 WD repeat domain 36". 

Further reading[edit]