The station began operation in 1980. Along with the SCERN simulcast based in Columbia, WJWJ occasionally broke off to air local shows from SCETV's studios in Beaufort.
In 2001, WJWJ was the first SCERN station to switch to an all-news format as both WSVH in Savannah and WSCI in Charleston provided the entire WJWJ listening area with classical music. However, with the change in formats, all local programming ended, and WJWJ's entire schedule is now fed from Columbia. It is the only NPR news/talk station in the area.